一种缺乏溶血活性的C4B基因座产物。
A product of the C4B locus lacking hemolytic activity.
作者信息
Suzuki K, O'Neill G J, Matsumoto H
出版信息
Hum Genet. 1986 Jun;73(2):101-3. doi: 10.1007/BF00291595.
PMID:3522406
Abstract
An unusual C4B allotype, C4B 4I, was identified in a study of C4 polymorphism in Japanese. This variant was defined as C4B using a murine monoclonal antibody specific for the C4d region of C4B. Hemolytic assay, however, revealed that the C4 variant, C4 BI was hemolytically inactive in contrast to other well-defined C4B locus products.
摘要
在一项对日本人C4多态性的研究中，发现了一种不寻常的C4B同种异型，即C4B 4I。使用对C4B的C4d区域具有特异性的鼠单克隆抗体，将该变体定义为C4B。然而，溶血试验表明，与其他明确的C4B基因座产物相比，C4变体C4 BI没有溶血活性。
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