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Epidemiological, clinical, and laboratory findings for patients of different age groups with confirmed coronavirus disease 2019 (COVID-19) in a hospital in Saudi Arabia.沙特阿拉伯一家医院中不同年龄组确诊 2019 年冠状病毒病(COVID-19)患者的流行病学、临床和实验室结果。
PLoS One. 2021 Apr 29;16(4):e0250955. doi: 10.1371/journal.pone.0250955. eCollection 2021.
2
Complete Blood-count-based Inflammatory Score (CBCS) of COVID-19 Patients at Tertiary Care Center.基于全血细胞计数的 COVID-19 患者炎症评分(CBCS)在三级医疗中心。
Altern Ther Health Med. 2021 Jun;27(S1):18-24.
3
Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission.全球 COVID-19 荟萃分析显示,男性性别是死亡和 ICU 入院的风险因素。
Nat Commun. 2020 Dec 9;11(1):6317. doi: 10.1038/s41467-020-19741-6.
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Clinical, epidemiological, and laboratory characteristics of mild-to-moderate COVID-19 patients in Saudi Arabia: an observational cohort study.沙特阿拉伯轻度至中度 COVID-19 患者的临床、流行病学和实验室特征:一项观察性队列研究。
Eur J Med Res. 2020 Nov 25;25(1):61. doi: 10.1186/s40001-020-00462-x.
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COVID-19 mortality risk for older men and women.COVID-19 对老年男性和女性的死亡率风险。
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沙特阿拉伯纳季兰的哈立德国王医院的 COVID-19 患者的血液学检查结果。

Hematological Findings among COVID-19 Patients Attending King Khalid Hospital at Najran, Kingdom of Saudi Arabia.

机构信息

College of Health Sciences, Saudi Electronic University, Riyadh, Saudi Arabia.

Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, Kosti, Sudan.

出版信息

Biomed Res Int. 2022 Feb 16;2022:4620037. doi: 10.1155/2022/4620037. eCollection 2022.

DOI:10.1155/2022/4620037
PMID:35224093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8865990/
Abstract

COVID-19 is a global pandemic viral infection that has affected millions worldwide. Limited data is available on the effect of COVID-19 on hematological parameters in Saudi Arabia. This study is aimed at examining the role of hematological parameters among COVID-19 patients admitted to King Khalid Hospital in Najran, Saudi Arabia. This is a retrospective, hospital-based study of 514 cases who were recruited during August to October 2020. 257 COVID-19 patients formed the study group, and a further 257 negative subjects formed the control group. Anemia was significantly elevated in positive subjects over controls (respectively, 64.2% and 35.8%), with patients 2.5 times more likely to be anemic ( < 0.01). Thrombocytopenia was higher in patients over controls (respectively, 62% and 38%), with patients ~1.7 times more likely to be thrombocytopenic ( < 0.01). Moreover, leukopenia was significantly higher in patients over controls (respectively, 71% and 29%), with positive subjects ~2.6 times more likely to be leukopenic. Our study results indicate that mild anemia associated with leukopenia may have diagnostic value for COVID-19. Careful assessment of hematological parameters, at baseline and throughout the disease path, will assist physicians in formulating personalized approaches to treatment and promptly offer intensive care to those in greater need.

摘要

新型冠状病毒肺炎(COVID-19)是一种全球性的病毒性传染病,已在全球范围内影响了数百万人。目前有关 COVID-19 对沙特阿拉伯人群血液学参数影响的数据有限。本研究旨在研究沙特阿拉伯纳季兰国王哈利德国王医院收治的 COVID-19 患者的血液学参数的作用。这是一项回顾性的基于医院的研究,共纳入了 514 例患者,他们是在 2020 年 8 月至 10 月期间招募的。257 例 COVID-19 患者为研究组,另外 257 例阴性患者为对照组。阳性组的贫血发生率明显高于对照组(分别为 64.2%和 35.8%),贫血患者的患病风险增加了 2.5 倍( < 0.01)。血小板减少症在患者中也高于对照组(分别为 62%和 38%),血小板减少症患者的患病风险增加了 1.7 倍( < 0.01)。此外,白细胞减少症在患者中也明显高于对照组(分别为 71%和 29%),白细胞减少症患者的患病风险增加了 2.6 倍。我们的研究结果表明,轻度贫血伴白细胞减少可能对 COVID-19 具有诊断价值。在疾病发生的整个过程中,仔细评估血液学参数将有助于医生制定个性化的治疗方法,并及时为那些病情更严重的患者提供重症监护。