Stuyvesant, New York, New York 10282.
Department of Biochemistry, University of California, Los Angeles, Los Angeles, California 90095.
J Food Prot. 2022 Jun 1;85(6):918-923. doi: 10.4315/JFP-21-427.
Roasting coffee results in not only the creation of carcinogens such as acrylamide, furan, and polycyclic aromatic hydrocarbons but also the elimination of carcinogens in raw coffee beans, such as endotoxins, preservatives, or pesticides, by burning off. However, it has not been determined whether the concentrations of these carcinogens are sufficient to make either light or dark roast coffee more carcinogenic in a living organism. An Ames test was conducted on light, medium, and dark roast coffee from three origins. We found that lighter roast coffee shows higher mutagenicity, which is reduced to the control level in dark roast coffee varieties, indicating that the roasting process is not increasing mutagenic potential but is beneficial to eliminating the existing carcinogens in raw coffee beans. This result suggests that dark roast coffee is safer and promotes further studies of the various carcinogens in raw coffee that have been burned off.
烘焙咖啡豆不仅会产生丙烯酰胺、糠醛和多环芳烃等致癌物质,还会通过燃烧去除生咖啡豆中的内毒素、防腐剂或农药等致癌物质。然而,目前尚不清楚这些致癌物质的浓度是否足以使浅色或深色烘焙咖啡在生物体中更具致癌性。我们对来自三个产地的浅、中、深烘焙咖啡进行了艾姆斯试验。我们发现,浅色烘焙咖啡显示出更高的致突变性,而在深色烘焙咖啡品种中则降低到对照水平,这表明烘焙过程不会增加致突变潜力,而是有利于消除生咖啡豆中现有的致癌物质。这一结果表明,深色烘焙咖啡更安全,并促使进一步研究已被烧掉的生咖啡豆中的各种致癌物质。