O'Loughlin S, Schroeter A L, Jordon R E
Arch Dermatol. 1978 Jun;114(6):879-83.
Twelve of 54 patients with systemic lupus erythematosus (SLE) had nonpuric, chronic urticaria-like lessions. Skin biopsy of the lesions was performed in 11 cases, and nine showed necrotizing vasculitis. The 54 patients, in general, had severe disease, and laboratory and clinical data suggested a postivite relationship between the urticaria-like lesions and disease severity. There was no consistent relationship between the course of the urticaria-like lesions and the serologic findings and clinical activity of the SLE. The frequency and importance of urticaria-like lesions in SLE deserve further study.
54例系统性红斑狼疮（SLE）患者中有12例出现非紫癜性慢性荨麻疹样皮损。对其中11例患者的皮损进行了皮肤活检，9例显示为坏死性血管炎。总体而言，这54例患者病情严重，实验室和临床数据提示荨麻疹样皮损与疾病严重程度呈正相关。荨麻疹样皮损的病程与SLE的血清学检查结果及临床活动度之间无一致的相关性。SLE中荨麻疹样皮损的发生率及重要性值得进一步研究。
