King Fahad Medical City, Riyadh, Saudi Arabia.
J Med Case Rep. 2022 Mar 1;16(1):86. doi: 10.1186/s13256-022-03306-w.
Calcinosis cutis is a rare condition, characterized by an accumulation of calcium salts in the skin and subcutaneous tissue. There are several types of this condition, including dystrophic, metastatic, idiopathic, calciphylaxis, and iatrogenic calcinosis cutis. The type related to our case is iatrogenic calcinosis cutis, and one its possible causes is calcium intravenous infusion. Physicians should be aware of this condition when giving calcium infusion.
Here we report the case of a 9-month-old Arabic - Saudi baby boy, who presented with abnormal movement for 1 day. Upon further investigation, his abnormal movement was found to be a manifestation of hypocalcemia and vitamin D deficiency. He was treated with intravenous calcium gluconate. Later, he had a treatment-related complication of intravenous calcium at the site of venipuncture causing swelling, which was initially soft but progressed to hard, over the left hand. Eventually, he was diagnosed with a case of iatrogenic calcinosis cutis due to intravenous calcium treatment.
There are multiple differential diagnoses of calcinosis cutis, as it resembles many other conditions. Careful history-taking, physical examination, and other investigations, such as radiological investigations, will aid in reaching a more accurate diagnosis and, thus, early treatment and intervention. Frequently checking the intravenous line and diluting the intravenous calcium may help reduce the occurrence of iatrogenic calcinosis cutis.
皮肤钙化症是一种罕见的疾病,其特征是钙盐在皮肤和皮下组织中积聚。这种疾病有几种类型,包括营养不良性、转移性、特发性、钙化性尿毒症和医源性皮肤钙化症。与我们的病例相关的类型是医源性皮肤钙化症,其可能的原因之一是静脉输注钙。当给予钙输注时,医生应该意识到这种情况。
这里我们报告了一例 9 个月大的阿拉伯-沙特婴儿男孩,他因 1 天的异常运动而就诊。进一步检查发现,他的异常运动表现为低钙血症和维生素 D 缺乏。他接受了静脉注射葡萄糖酸钙治疗。后来,他在静脉穿刺部位出现了与治疗相关的并发症,导致左手肿胀,起初是软的,但后来变硬了。最终,他被诊断为医源性皮肤钙化症,原因是静脉注射钙治疗。
皮肤钙化症有多种鉴别诊断,因为它类似于许多其他疾病。仔细的病史询问、体格检查和其他检查,如影像学检查,将有助于做出更准确的诊断,从而进行早期治疗和干预。经常检查静脉输液管并稀释静脉钙可能有助于减少医源性皮肤钙化症的发生。