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医源性皮肤钙化症:一种罕见的细胞学诊断。

Iatrogenic calcinosis cutis: A rare cytological diagnosis.

作者信息

Sawke Gopal Krishna, Rai Tina, Sawke Nilima

机构信息

Department of Pathology, People's College of Medical Sciences and Research Centre, Bhopal, Madhya Pradesh, India.

出版信息

J Cytol. 2016 Jul-Sep;33(3):166-168. doi: 10.4103/0970-9371.177146.

Abstract

Calcinosis cutis is an uncommon condition characterized by the deposition of calcium salts in the subcutaneous tissues of the body. Calcifications can also occur in a variety of other clinical settings and can be subjected to fine-needle aspiration (FNA). Since cutaneous calcific deposits may clinically mimic a tumor, it is feasible to diagnose them by FNA cytology (FNAC). We reported a case of calcinosis cutis by FNA in a 36-year-old male who presented with a solitary subcutaneous nodule in cubital fossa. Smears showed amorphous granular material consistent with calcium and occasional histiocytes. The diagnosis was confirmed when cytosmears were subjected to a special stain such as the von Kossa stain.

摘要

皮肤钙化症是一种罕见的病症,其特征是身体皮下组织中钙盐沉积。钙化也可发生在多种其他临床情况下,并且可以进行细针穿刺抽吸(FNA)。由于皮肤钙化沉积物在临床上可能类似肿瘤,因此通过FNA细胞学检查(FNAC)来诊断它们是可行的。我们报告了一例36岁男性通过FNA诊断为皮肤钙化症的病例,该患者在肘窝处出现一个孤立的皮下结节。涂片显示有无定形颗粒物质,与钙一致,偶尔可见组织细胞。当细胞涂片进行诸如冯·科萨染色等特殊染色时,诊断得到证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/120e/4995877/fcf4e51aebb2/JCytol-33-166-g001.jpg

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本文引用的文献

1
Calcinosis cutis: part I. Diagnostic pathway.皮肤钙化病:第一部分。诊断途径。
J Am Acad Dermatol. 2011 Jul;65(1):1-12; quiz 13-4. doi: 10.1016/j.jaad.2010.08.038.
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Tumoral calcinosis.肿瘤性钙化
Indian J Dermatol Venereol Leprol. 2005 Jul-Aug;71(4):293-4. doi: 10.4103/0378-6323.16631.
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Calcinosis cutis: diagnosis by aspiration cytology--a case report.皮肤钙质沉着症:通过细针穿刺抽吸活检诊断——病例报告
Diagn Cytopathol. 1999 Sep;21(3):200-2. doi: 10.1002/(sici)1097-0339(199909)21:3<200::aid-dc11>3.0.co;2-4.

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