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本文引用的文献

1
Risk of 30-Day Hospital Readmission Among Patients Discharged to Skilled Nursing Facilities: Development and Validation of a Risk-Prediction Model.患者出院至护理院 30 天内再入院风险:风险预测模型的建立与验证。
J Am Med Dir Assoc. 2019 Apr;20(4):444-450.e2. doi: 10.1016/j.jamda.2019.01.137. Epub 2019 Mar 7.
2
Predicting Potential Adverse Events During a Skilled Nursing Facility Stay: A Skilled Nursing Facility Prognosis Score.预测熟练护理机构住院期间的潜在不良事件:熟练护理机构预后评分。
J Am Geriatr Soc. 2018 May;66(5):930-936. doi: 10.1111/jgs.15324. Epub 2018 Mar 2.
3
Impact of a Connected Care Model on 30-Day Readmission Rates from Skilled Nursing Facilities.连续护理模式对专业护理机构30天再入院率的影响。
J Hosp Med. 2017 Apr;12(4):238-244. doi: 10.12788/jhm.2710.
4
End-of-Life Care Transition Patterns of Medicare Beneficiaries.医疗保险受益人的临终关怀过渡模式
J Am Geriatr Soc. 2017 Jul;65(7):1406-1413. doi: 10.1111/jgs.14891. Epub 2017 Apr 3.
5
Effect of the Goals of Care Intervention for Advanced Dementia: A Randomized Clinical Trial.晚期痴呆症护理目标干预的效果:一项随机临床试验
JAMA Intern Med. 2017 Jan 1;177(1):24-31. doi: 10.1001/jamainternmed.2016.7031.
6
Palliative Care Consultations in Nursing Homes and Reductions in Acute Care Use and Potentially Burdensome End-of-Life Transitions.养老院中的姑息治疗咨询与急性护理使用的减少以及潜在繁重的临终过渡情况
J Am Geriatr Soc. 2016 Nov;64(11):2280-2287. doi: 10.1111/jgs.14469. Epub 2016 Sep 19.
7
Medicare Program; Prospective Payment System and Consolidated Billing for Skilled Nursing Facilities (SNFs) for FY 2016, SNF Value-Based Purchasing Program, SNF Quality Reporting Program, and Staffing Data Collection. Final Rule.医疗保险计划;2016财年熟练护理设施(SNFs)的前瞻性支付系统和合并计费、SNF基于价值的采购计划、SNF质量报告计划以及人员配置数据收集。最终规则。
Fed Regist. 2015 Aug 4;80(149):46389-477.
8
Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): the TRIPOD statement.透明报告个体预后或诊断的多变量预测模型(TRIPOD):TRIPOD 声明。
Ann Intern Med. 2015 Jan 6;162(1):55-63. doi: 10.7326/M14-0697.
9
Update in hospital palliative care.医院姑息治疗的最新进展。
J Hosp Med. 2013 Dec;8(12):715-20. doi: 10.1002/jhm.2110. Epub 2013 Nov 8.
10
30-day hospital readmission of older adults using care transitions after hospitalization: a pilot prospective cohort study.老年人在出院后使用过渡期护理的 30 天住院再入院率:一项前瞻性试点队列研究。
Clin Interv Aging. 2013;8:729-36. doi: 10.2147/CIA.S44390. Epub 2013 Jun 18.

转至专业护理机构的患者6个月死亡率风险预测模型

Risk Prediction Model for 6-Month Mortality for Patients Discharged to Skilled Nursing Facilities.

作者信息

Chandra Anupam, Takahashi Paul Y, McCoy Rozalina G, Thorsteinsdottir Bjoerg, Hanson Gregory J, Chaudhry Rajeev, Rahman Parvez A, Storlie Curtis B, Murphree Dennis H

机构信息

Division of Community Internal Medicine, Mayo Clinic, Rochester, MN, USA; Division of Geriatric Medicine and Gerontology, Mayo Clinic, Rochester, MN, USA.

Division of Community Internal Medicine, Mayo Clinic, Rochester, MN, USA; Division of Geriatric Medicine and Gerontology, Mayo Clinic, Rochester, MN, USA.

出版信息

J Am Med Dir Assoc. 2022 Aug;23(8):1403-1408. doi: 10.1016/j.jamda.2022.01.069. Epub 2022 Feb 25.

DOI:10.1016/j.jamda.2022.01.069
PMID:35227666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9378493/
Abstract

OBJECTIVE

Hospitalized patients discharged to skilled nursing facilities (SNFs) for post-acute care are at high risk for adverse outcomes. Yet, absence of effective prognostic tools hinders optimal care planning and decision making. Our objective was to develop and validate a risk prediction model for 6-month all-cause death among hospitalized patients discharged to SNFs.

DESIGN

Retrospective cohort study.

SETTING AND PARTICIPANTS

Patients discharged from 1 of 2 hospitals to 1 of 10 SNFs for post-acute care in an integrated health care delivery system between January 1, 2009, and December 31, 2016.

METHODS

Gradient-boosting machine modeling was used to predict all-cause death within 180 days of hospital discharge with use of patient demographic characteristics, comorbidities, pattern of prior health care use, and clinical parameters from the index hospitalization. Area under the receiver operating characteristic curve (AUC) was assessed for out-of-sample observations under 10-fold cross-validation.

RESULTS

We identified 9803 unique patients with 11,647 hospital-to-SNF discharges [mean (SD) age, 80.72 (9.71) years; female sex, 61.4%]. These discharges involved 9803 patients alive at 180 days and 1844 patients who died between day 1 and day 180 of discharge. Age, comorbid burden, health care use in prior 6 months, abnormal laboratory parameters, and mobility status during hospital stay were the most important predictors of 6-month death (model AUC, 0.82).

CONCLUSION AND IMPLICATIONS

We derived a robust prediction model with parameters available at discharge to SNFs to calculate risk of death within 6 months. This work may be useful to guide other clinicians wishing to develop mortality prediction instruments specific to their post-acute SNF populations.

摘要

目的

出院后入住专业护理机构(SNFs)接受急性后期护理的住院患者发生不良结局的风险很高。然而,缺乏有效的预后工具阻碍了最佳护理计划和决策制定。我们的目标是开发并验证一个针对出院后入住SNFs的住院患者6个月全因死亡的风险预测模型。

设计

回顾性队列研究。

设置和参与者

2009年1月1日至2016年12月31日期间,在一个综合医疗保健服务系统中,从2家医院中的1家出院后入住10家SNFs中的1家接受急性后期护理的患者。

方法

使用梯度提升机模型,利用患者的人口统计学特征、合并症、既往医疗保健使用模式以及本次住院的临床参数,预测出院后180天内的全因死亡。在10倍交叉验证下,对样本外观察结果评估受试者工作特征曲线下面积(AUC)。

结果

我们确定了9803名独特患者,他们有11647次从医院到SNFs的出院记录[平均(标准差)年龄,80.72(9.71)岁;女性,61.4%]。这些出院记录涉及9803名在180天时存活的患者和1844名在出院第1天至第180天之间死亡的患者。年龄、合并症负担、过去6个月的医疗保健使用情况、实验室参数异常以及住院期间的活动状态是6个月死亡的最重要预测因素(模型AUC,0.82)。

结论及意义

我们推导出了一个强大的预测模型,该模型使用出院时可获得的参数来计算入住SNFs患者6个月内死亡风险。这项工作可能有助于指导其他希望开发针对其急性后期SNFs人群的死亡率预测工具的临床医生。