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General Anesthesia With Successful Immediate Post-operative Extubation for Sarcoma Excision in a 61-Year-Old Male With Kennedy's Disease.一名患有肯尼迪病的61岁男性肉瘤切除术后即刻成功拔管的全身麻醉
Cureus. 2022 Feb 6;14(2):e21956. doi: 10.7759/cureus.21956. eCollection 2022 Feb.
2
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Case series: anesthetic management of patients with spinal and bulbar muscular atrophy (Kennedy's disease).病例系列:脊髓延髓肌肉萎缩症(肯尼迪病)患者的麻醉管理
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引用本文的文献

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Anesthetic management of a patient with spinal and bulbar muscular atrophy (Kennedy's disease) : Case report with brief literature review.脊髓延髓肌萎缩症(肯尼迪病)患者的麻醉管理:病例报告及简要文献综述
Anaesthesiologie. 2024 Aug;73(8):531-534. doi: 10.1007/s00101-024-01430-4. Epub 2024 Jun 28.

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A Missing Voice: The Lingual Complex and Osteopathic Manual Medicine in the Context of Five Osteopathic Models.一个缺失的声音:五种整骨疗法模型背景下的舌复合体与整骨手法医学
Cureus. 2021 Oct 11;13(10):e18658. doi: 10.7759/cureus.18658. eCollection 2021 Oct.
2
Kennedy's disease (spinal and bulbar muscular atrophy): a clinically oriented review of a rare disease.肯尼迪病(脊髓延髓肌萎缩症):一种罕见疾病的临床综述。
J Neurol. 2019 Mar;266(3):565-573. doi: 10.1007/s00415-018-8968-7. Epub 2018 Jul 13.
3
The use of sugammadex in a patient with Kennedy's disease under general anesthesia.在全身麻醉下,舒更葡糖钠在一名肯尼迪病患者中的应用。
Saudi J Anaesth. 2014 Jul;8(3):418-20. doi: 10.4103/1658-354X.136640.
4
Perspectives of Kennedy's disease.肯尼迪病的观点。
J Neurol Sci. 2010 Nov 15;298(1-2):1-10. doi: 10.1016/j.jns.2010.08.025. Epub 2010 Sep 16.
5
Case series: anesthetic management of patients with spinal and bulbar muscular atrophy (Kennedy's disease).病例系列:脊髓延髓肌肉萎缩症(肯尼迪病)患者的麻醉管理
Can J Anaesth. 2009 Feb;56(2):136-41. doi: 10.1007/s12630-008-9018-1. Epub 2009 Jan 10.
6
Laryngospasm: an underdiagnosed symptom of X-linked spinobulbar muscular atrophy.喉痉挛:X连锁脊髓延髓肌萎缩症的一种未被充分诊断的症状。
Neurology. 2005 Feb 22;64(4):753-4. doi: 10.1212/01.WNL.0000151978.74467.E7.
7
Use of epidural anaesthesia for surgery in a patient with Kennedy's disease.肯尼迪病患者手术中硬膜外麻醉的应用。
Br J Anaesth. 2004 Mar;92(3):432-3. doi: 10.1093/bja/aeh068. Epub 2004 Jan 22.
8
Epidural anesthesia and pulmonary function in a patient with amyotrophic lateral sclerosis.肌萎缩侧索硬化症患者的硬膜外麻醉与肺功能
Anesth Analg. 1996 Oct;83(4):878-9. doi: 10.1097/00000539-199610000-00040.
9
Kennedy's disease: a clinicopathologic correlation with mutations in the androgen receptor gene.
Neurology. 1993 Apr;43(4):791-4. doi: 10.1212/wnl.43.4.791.
10
Epidural anesthesia for patients with amyotrophic lateral sclerosis.
Anesth Analg. 1989 Mar;68(3):410-2.

一名患有肯尼迪病的61岁男性肉瘤切除术后即刻成功拔管的全身麻醉

General Anesthesia With Successful Immediate Post-operative Extubation for Sarcoma Excision in a 61-Year-Old Male With Kennedy's Disease.

作者信息

Evans Raymond, Escher Allan R, Nahrwold Daniel A, Hoffman Jamie P

机构信息

Anesthesiology, Moffitt Cancer Center and Research Institute, Tampa, USA.

Anesthesiology/Pain Medicine, Moffitt Cancer Center and Research Institute, Tampa, USA.

出版信息

Cureus. 2022 Feb 6;14(2):e21956. doi: 10.7759/cureus.21956. eCollection 2022 Feb.

DOI:10.7759/cureus.21956
PMID:35228980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8865878/
Abstract

Kennedy's disease (KD), also known as spinal and bulbar muscular atrophy (SBMA), is a rare, X-linked recessive androgen receptor gene mutation affecting approximately one in 40,000 males. A prominent anesthetic concern in patients with KD is their ability to maintain a patent airway following general anesthesia. We present the case of a 61-year-old man with a history of KD presenting for a left thigh sarcoma excision. The patient received a general anesthetic with endotracheal tube placement, was extubated in the operating room upon completion of the surgery, and had an uneventful post-operative course.

摘要

肯尼迪病(KD),又称脊髓延髓肌肉萎缩症(SBMA),是一种罕见的X连锁隐性雄激素受体基因突变疾病,约每40000名男性中就有1人患病。KD患者一个突出的麻醉问题是全身麻醉后维持气道通畅的能力。我们报告一例61岁有KD病史的男性患者,因左大腿肉瘤切除术前来就诊。患者接受了气管插管全身麻醉,手术结束后在手术室拔管,术后过程顺利。