• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新西兰羔羊皮肤特征的遗传变异。

Genetic variation in skin traits in New Zealand lambs.

机构信息

AgResearch Ltd, Invermay Agricultural Centre, Mosgiel, New Zealand.

New Zealand Leather and Shoe Research Association (Inc.), Palmerston North, New Zealand.

出版信息

J Sci Food Agric. 2022 Aug 30;102(11):4813-4819. doi: 10.1002/jsfa.11844. Epub 2022 Mar 9.

DOI:10.1002/jsfa.11844
PMID:35229322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9546359/
Abstract

BACKGROUND

This study explored the genetic variability in the New Zealand sheep population for economically important skin traits. Skins were collected at slaughter from two progeny test flocks, resulting in 725 skins evaluated for grain strain, flatness, crust leather strength and overall suitability for shoe leather. DNA profiles collected from skins post-slaughter were matched to individual animals using previously collected high-density genotypes.

RESULTS

Considerable phenotypic variation for skin traits was observed, with around 40% of the skins being identified as suitable for high-value shoe leather production. Several key traits associated with leather production, including flatness, tear strength, grain strength and grain strain were found to be moderate to highly heritable (h = 0.28-0.82). There were no major significant genome-wide association study (GWAS) peaks associated with many of the traits examined, however, one single-nucleotide polymorphism (SNP) reached significance for the flatness of the skin over the hindquarters.

CONCLUSION

This research confirms that suitable lamb skins can be bred for use as high-value shoe leather. While moderately to highly heritable, skin traits in New Zealand lambs appear to be polygenic with no genes of major effect underlaying the traits of interest. Given the complex nature of these traits, the identification and selection of animals with higher-value skins may be enabled by geomic selection. © 2022 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

摘要

背景

本研究探索了新西兰绵羊群体在具有经济重要性的皮肤性状方面的遗传变异性。屠宰时从两个后裔测试群中收集皮肤,共评估了 725 个皮样的粒面强度、平整度、革皮强度和整体制鞋适用性。屠宰后从皮样中收集的 DNA 图谱使用先前收集的高密度基因型与个体动物进行匹配。

结果

观察到皮肤性状存在相当大的表型变异,大约 40%的皮样被鉴定为适合生产高价值鞋革。与皮革生产相关的几个关键性状,包括平整度、撕裂强度、粒面强度和粒面应变,被发现具有中等至高度的遗传力(h = 0.28-0.82)。许多检查的性状都没有与主要显著全基因组关联研究(GWAS)峰相关,但一个单核苷酸多态性(SNP)与皮肤后半部的平整度显著相关。

结论

这项研究证实,适合的羔羊皮可以通过选育用于生产高价值的鞋革。虽然皮肤性状具有中等至高度的遗传力,但新西兰羔羊的皮肤性状似乎是多基因的,没有主要基因影响所关注性状的遗传基础。鉴于这些性状的复杂性,通过基因组选择可能能够识别和选择具有更高价值皮肤的动物。© 2022 作者。《食品科学杂志》由 John Wiley & Sons Ltd 代表化学工业协会出版。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf4d/9546359/ff2919d1d2d9/JSFA-102-4813-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf4d/9546359/daebb44bff53/JSFA-102-4813-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf4d/9546359/ff2919d1d2d9/JSFA-102-4813-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf4d/9546359/daebb44bff53/JSFA-102-4813-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf4d/9546359/ff2919d1d2d9/JSFA-102-4813-g002.jpg

相似文献

1
Genetic variation in skin traits in New Zealand lambs.新西兰羔羊皮肤特征的遗传变异。
J Sci Food Agric. 2022 Aug 30;102(11):4813-4819. doi: 10.1002/jsfa.11844. Epub 2022 Mar 9.
2
Effects of Psoroptes ovis infection and its control with an ivermectin controlled-release capsule on growing sheep. 2. Evaluation of wool production and leather value.绵羊痒螨感染及其用伊维菌素控释胶囊控制对生长绵羊的影响。2. 羊毛产量和皮革价值评估。
Vet Parasitol. 2000 Jul 24;91(1-2):119-28. doi: 10.1016/s0304-4017(00)00244-2.
3
Genome-wide association study of lung lesions and pleurisy in New Zealand lambs.新西兰绵羊肺部病变和胸膜炎的全基因组关联研究。
J Anim Sci. 2018 Nov 21;96(11):4512-4520. doi: 10.1093/jas/sky323.
4
Genetic parameter analysis of bareness and tail traits in New Zealand sheep.新西兰绵羊光裸和尾巴性状的遗传参数分析。
J Anim Sci. 2023 Jan 3;101. doi: 10.1093/jas/skad161.
5
Genomic prediction and genome-wide association study for dagginess and host internal parasite resistance in New Zealand sheep.新西兰绵羊的凶恶程度和宿主内部寄生虫抗性的基因组预测及全基因组关联研究
BMC Genomics. 2015 Nov 17;16:958. doi: 10.1186/s12864-015-2148-2.
6
Pre-slaughter, slaughter and post-slaughter defects of skins and hides at the Sheba Tannery and Leather Industry, Tigray region, northern Ethiopia.埃塞俄比亚北部提格雷地区谢巴制革厂及皮革工业中,生皮和皮革的宰前、屠宰及宰后缺陷。
Onderstepoort J Vet Res. 2015 Aug 21;82(1):E1-7. doi: 10.4102/ojvr.v82i1.931.
7
Integration of a single-step genome-wide association study with a multi-tissue transcriptome analysis provides novel insights into the genetic basis of wool and weight traits in sheep.将全基因组关联研究与多组织转录组分析相结合,为绵羊羊毛和体重性状的遗传基础提供了新的见解。
Genet Sel Evol. 2021 Jun 30;53(1):56. doi: 10.1186/s12711-021-00649-8.
8
A conditional multi-trait sequence GWAS discovers pleiotropic candidate genes and variants for sheep wool, skin wrinkle and breech cover traits.条件多性状序列 GWAS 发现了绵羊羊毛、皮肤褶皱和臀盖性状的多效候选基因和变异。
Genet Sel Evol. 2021 Jul 8;53(1):58. doi: 10.1186/s12711-021-00651-0.
9
Genetic parameters for production traits in New Zealand dual-purpose sheep, with an emphasis on dagginess.新西兰肉毛兼用型绵羊生产性状的遗传参数分析,重点研究产绒量。
J Anim Sci. 2012 May;90(5):1411-20. doi: 10.2527/jas.2011-4163. Epub 2011 Nov 18.
10
Phenotypic variation and genome-wide association studies of main culm panicle node number, maximum node production rate, and degree-days to heading in rice.水稻主茎穗颈节数、最大穗颈节间伸长速率和生育天数的表型变异及全基因组关联研究。
BMC Genomics. 2022 May 23;23(1):390. doi: 10.1186/s12864-022-08629-y.

引用本文的文献

1
Assessment of morphological features of skin and hair cover of Karakul lambs (South of Kazakhstan).卡拉库尔羔羊(哈萨克斯坦南部)皮肤和毛发特征的评估。
Trop Anim Health Prod. 2023 Nov 20;55(6):406. doi: 10.1007/s11250-023-03836-5.

本文引用的文献

1
Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services.将动物 QTLdb 和 CorrDB 带入未来:迎接新挑战,提供更新的服务。
Nucleic Acids Res. 2022 Jan 7;50(D1):D956-D961. doi: 10.1093/nar/gkab1116.
2
Genetic diversity of a New Zealand multi-breed sheep population and composite breeds' history revealed by a high-density SNP chip.高密度SNP芯片揭示新西兰多品种绵羊群体的遗传多样性及复合品种的历史
BMC Genet. 2017 Mar 14;18(1):25. doi: 10.1186/s12863-017-0492-8.
3
A high throughput single nucleotide polymorphism multiplex assay for parentage assignment in New Zealand sheep.
一种高通量单核苷酸多态性多重分析方法,用于新西兰绵羊的亲子关系鉴定。
PLoS One. 2014 Apr 16;9(4):e93392. doi: 10.1371/journal.pone.0093392. eCollection 2014.
4
Investigations into the GDF8 g+6723G-A polymorphism in New Zealand Texel sheep.新西兰特克塞尔羊GDF8基因g+6723G-A多态性的研究
J Anim Sci. 2009 Jun;87(6):1856-64. doi: 10.2527/jas.2008-1508. Epub 2009 Feb 27.
5
GenABEL: an R library for genome-wide association analysis.GenABEL:一个用于全基因组关联分析的R语言库。
Bioinformatics. 2007 May 15;23(10):1294-6. doi: 10.1093/bioinformatics/btm108. Epub 2007 Mar 23.
6
Principal components analysis corrects for stratification in genome-wide association studies.主成分分析可校正全基因组关联研究中的分层现象。
Nat Genet. 2006 Aug;38(8):904-9. doi: 10.1038/ng1847. Epub 2006 Jul 23.
7
A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep.一种在肌肉生长抑制素基因中产生潜在异常微小RNA靶位点的突变会影响绵羊的肌肉发育。
Nat Genet. 2006 Jul;38(7):813-8. doi: 10.1038/ng1810. Epub 2006 Jun 4.
8
Prediction of total genetic value using genome-wide dense marker maps.利用全基因组密集标记图谱预测总遗传值。
Genetics. 2001 Apr;157(4):1819-29. doi: 10.1093/genetics/157.4.1819.
9
Productive performance of Dorper sheep.杜泊绵羊的生产性能
Small Rumin Res. 2000 May 1;36(2):119-135. doi: 10.1016/s0921-4488(99)00156-x.