School of Veterinary Medicine, Positivo University, Curitiba, Paraná, Brazil.
Institute of Collective Health, Federal University of Bahia, Salvador, Bahia, Brazil.
Vet Med Sci. 2022 Mar;8(2):530-536. doi: 10.1002/vms3.704. Epub 2022 Mar 1.
Individuals with hoarding disorder (HD) presented a persistent difficulty in detaching from objects and/or animals. Unhealthy conditions, frequently found in cases of animal HD (AHD), may favour environmental contamination and the spread of zoonotic pathogens. Despite that, only one study of zoonotic diseases in individuals with AHD and their companion animals has been conducted to date.
This study aimed to assess the seroprevalence of anti-Leptospira spp. antibodies in individuals with AHD and their dogs in a major city of Southern Brazil.
Blood samples were obtained from 264 dogs (21 households) and 19 individuals with AHD (11 households) and tested by microscopic agglutination test.
All human samples were seronegative. Seropositivity was found in 16/264 (6.1%; CI 95% 3.3-9.6%) dogs from 11/21 (52.38%) households, with titres ranging from 100 up to 400, and Copenhageni (10/16; 62.5%) was the most frequent serovar. Surprisingly, seropositivity of hoarded dogs found herein was among the lowest reportedly observed in other dog populations of Brazil. Two epidemiological variables were significantly associated with seropositivity in dogs: the presence of cat hoarding (p = 0.004) and the report of flood occurrence in the household (p = 0.031).
No individuals with AHD were seropositive, and besides the lower seroprevalence of dogs, they probably had contact with Leptospira spp. at some point in their life. Since dogs can be considered potential sentinels in leptospirosis, public health programs must become aware of the risk of leptospirosis cases in households of individuals with AHD and nearby communities.
囤积症患者（HD）在与物品和/或动物分离方面存在持久的困难。在动物囤积症（AHD）病例中经常发现的不健康状况可能有利于环境污染和人畜共患病原体的传播。尽管如此，迄今为止，只有一项关于 AHD 患者及其伴侣动物的人畜共患病的研究。
本研究旨在评估巴西南部一个主要城市中 AHD 患者及其狗中抗钩端螺旋体 spp. 抗体的血清阳性率。
从 264 只狗（21 户）和 19 名 AHD 患者（11 户）中采集血液样本，并通过显微镜凝集试验进行检测。
所有人的样本均为血清阴性。在 11/21（52.38%）户中的 264 只狗（16/264；95%CI 3.3-9.6%）中发现血清阳性，滴度范围从 100 到 400，最常见的血清型是哥本哈根（10/16；62.5%）。令人惊讶的是，本文中发现的囤积狗的血清阳性率是巴西其他狗群中报道的最低水平之一。两个流行病学变量与狗的血清阳性显著相关：猫囤积（p=0.004）和家庭洪水发生报告（p=0.031）。
没有 AHD 患者呈血清阳性，除了狗的血清阳性率较低之外，他们一生中可能在某个时候接触过钩端螺旋体 spp.。由于狗可以被认为是钩端螺旋体病的潜在哨兵，公共卫生计划必须意识到 AHD 患者及其附近社区家庭中发生钩端螺旋体病病例的风险。
