Coordination of Gly-Tyr . Pd(II) complex to ATP and ADP nucleotides.

The coordination of the glycyl-L-tyrosinate . Pd(II) complex to adenosine 5' -diphosphate (ADP) and adenosine 5' -triphosphate (ATP) has been studied using 13C, 1H NMR and electronic spectral methods. Two dominant species have been found in solution, a monomeric ternary complex with Gly-Tyr . Pd(II) bound to the N-1 purine nitrogen and a dimer in which two dipeptide . Pd(II) complex molecules are coordinated to the nucleotide by N-1 and N-7 nitrogens. Monomeric ternary complexes having metal coordination to N-7 were not detected. The influence of the aromatic ring of tyrosine upon the chemical shifts for the bonded nucleotide molecule suggest that the plane of the purine ring and of the Gly-Tyr . Pd(II) complex are almost perpendicular to each other.