Hammoud Muhsen, Santos Charles Morphy D, Gois João Paulo
Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, Santo André, Brasil.
Centro de Ciências Naturais e Humanas, Laboratório de Sistemática e Diversidade, Universidade Federal do ABC, Santo André, Brasil.
J Comput Biol. 2022 Mar;29(3):292-303. doi: 10.1089/cmb.2021.0351. Epub 2022 Feb 25.
Current frameworks of side-by-side phylogenetic trees comparison face two issues: (1) accepting mainly binary trees as input and (2) assuming input trees having identical or highly overlapping taxa. However, cladistic comparative studies often lead with multiple nontotally resolved trees with nonidentical sets of taxa. We tackle these issues in this study, presenting the iPhyloC, an interactive web-based framework for comparing phylogenetic trees side by side. iPhyloC supports automatic identification of the common taxa in the input trees, comparison options between them, intuitive design, high usability, scalability to large trees, and cross-platform support. iPhyloC was tested using different trees and a supertree depicting the phylogenetic relationships within the insect order Diptera as examples.
（1）主要接受二叉树作为输入；（2）假设输入树具有相同或高度重叠的分类单元。然而，分支系统学比较研究常常涉及多个未完全解析的树，其分类单元集也不相同。在本研究中，我们解决了这些问题，提出了iPhyloC，这是一个基于网络的交互式框架，用于并排比较系统发育树。iPhyloC支持自动识别输入树中的共同分类单元、它们之间的比较选项、直观的设计、高可用性、对大树的可扩展性以及跨平台支持。我们以不同的树和描绘双翅目昆虫系统发育关系的超级树为例，对iPhyloC进行了测试。
