Department of Orthopaedic, The Affiliated Hospital of Medical School of Ningbo University, Ningbo, PR China.
Institute of Orthopaedics, Ningbo University, Ningbo, PR China.
Comput Methods Biomech Biomed Engin. 2022 Nov;25(15):1744-1756. doi: 10.1080/10255842.2022.2036979. Epub 2022 Mar 1.
Percutaneous vertebral augmentation (PVA) and percutaneous cement discoplasty (PCD) are two relatively new minimally invasive surgeries for symptomatic Schmorl's reported in recent decade. However, the clinical evidence for the effectiveness of these two surgeries is insufficient. The purpose of this study was to compare the biomechanical benefits and risks of the two surgeries in order to analyze their biomechanical differences and effectiveness. We reconstructed Five lumbar finite element models via computed tomography data, including control model, PVA-ideal model, PVA-nonideal model, PCD-ideal model, and PCD-nonideal model. The stress and strain of Schmorl's nodes, bone marrow edema zone (BMEZ), affected endplate, and the overall stability of segment were analyzed and compared. The validity of our models was confirmed. As a result, the PVA-ideal model can significantly reduce the stress of Schmorl's node and the strain of BMEZ, while this effect is inappreciable in PVA-nonideal model. The PCD-ideal model significantly reduced the strain of Schmorl's nodes and BMEZ, and significantly improve segmental stability, but also resulted in a significant increase in the stress of Schmorl's nodes, BMEZ and endplates. The PCD-nonideal model not only lacks blocking effect, but also sharply increases the strain of Schmorl's nodes and BMEZ. Thus, We recommend that both PVA and PCD surgeries in ideal distribution facilitated a more stable paranodular biomechanical microenvironment. However, due to the possibility of poor biomechanical outcomes caused by the non-ideal cement distribution, the non-ideal distribution of bone cement needs to be remedied in practice.
经皮椎体强化术(Percutaneous Vertebral Augmentation,PVA)和经皮椎间盘成形术(Percutaneous Cement Discoplasty,PCD)是近十年来报道的两种用于治疗有症状的 Schmorl's 结节的相对较新的微创手术。然而,这两种手术的有效性的临床证据还不够充分。本研究的目的是比较这两种手术的生物力学益处和风险,以分析它们的生物力学差异和有效性。我们通过 CT 数据重建了 5 个腰椎有限元模型,包括对照组模型、PVA-理想模型、PVA-非理想模型、PCD-理想模型和 PCD-非理想模型。分析和比较了 Schmorl's 结节、骨髓水肿区(Bone Marrow Edema Zone,BMEZ)、受累终板和节段整体稳定性的应力和应变。验证了我们模型的有效性。结果表明,PVA-理想模型可显著降低 Schmorl's 结节的应力和 BMEZ 的应变,而 PVA-非理想模型的效果不明显。PCD-理想模型可显著降低 Schmorl's 结节和 BMEZ 的应变,并显著改善节段稳定性,但也导致 Schmorl's 结节、BMEZ 和终板的应力显著增加。PCD-非理想模型不仅缺乏阻断作用,而且还急剧增加了 Schmorl's 结节和 BMEZ 的应变。因此,我们建议在理想分布的情况下,同时采用 PVA 和 PCD 手术可促成更稳定的结节旁生物力学微环境。然而,由于骨水泥非理想分布可能导致不良的生物力学结果,因此在实践中需要对骨水泥的非理想分布进行补救。