Niethammer D, Ostendorf P, Dopfer R, Klingebiel T
Klin Padiatr. 1986 May-Jun;198(3):155-70. doi: 10.1055/s-2008-1026872.
During recent years allogeneic bone marrow transplantation has been shown to be of clear value in the therapy of childhood leukemia. Presently the availability of an HLA identical sibling is necessary. Recently there are several attempts to pass this natural barrier. Possible alternatives are autologous transplantation or the use of an nonidentical family member or an identical unrelated person as a donor. Members of 17 bone marrow transplantation teams of the western world discussed during two days the various possibilities and the results obtained up to now. The paper reflects the state of the art as it was represented during the meeting. This is meant to help advice patients with leukemia and their parents on the further therapeutic proceedings.
近年来，异体骨髓移植已被证明在儿童白血病治疗中具有明确价值。目前，拥有人类白细胞抗原（HLA）匹配的同胞供者是必要的。最近，人们尝试突破这一自然障碍。可能的替代方法是自体移植，或使用HLA不匹配的家庭成员或匹配的非血缘供者作为供者。西方世界17个骨髓移植团队的成员在两天内讨论了各种可能性以及目前所取得的结果。本文反映了会议期间所呈现的最新技术水平。这旨在帮助为白血病患者及其父母提供有关进一步治疗程序的建议。
