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睾丸畸胎瘤中的异位眼组织:一例病例报告及文献综述

Ectopic ocular tissue in testicular teratoma: A case report and review of the literature.

作者信息

Alromaih Arwa Z, Fathaddin Amany A, Almater Abdullah I, Alkatan Hind M

机构信息

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Department of Pathology and Laboratory Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Int J Surg Case Rep. 2022 Mar;92:106854. doi: 10.1016/j.ijscr.2022.106854. Epub 2022 Feb 25.

DOI:10.1016/j.ijscr.2022.106854
PMID:35231735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8885984/
Abstract

INTRODUCTION AND IMPORTANCE

Teratoma is a common neoplasm in prepubertal and post-pubertal periods. It consists of various types of tissues arising from different germinal layers, endoderm, mesoderm, and ectoderm. Ectopic ocular tissue is a rare phenomenon, with only few reported cases in other locations.

CASE PRESENTATION

This is a 10-month-old boy who presented with a painless scrotal mass. Following orchidectomy, the excised mass confirmed the presence of uveal and retinal tissues originating in a benign testicular teratoma by histopathological examination.

DISCUSSION

Choroidal and retinal tissue are the most frequently encountered ectopic ocular tissue, while the least observed tissue is the lens. Most of the reported cases of ectopic ocular tissue present in ovarian teratomas. The only 2 previously reported cases of ocular-like tissue in testicular teratoma lack well-defined medullary epithelium, uveal, and retinal tissue as in our case.

CONCLUSION

To our knowledge, developing ocular tissue in a testicular teratoma is extremely rare. Herein we report a unique case with mature defined ocular tissue within a testicular teratoma in an infant, which should not be overlooked.

摘要

引言与重要性

畸胎瘤是青春期前和青春期后常见的肿瘤。它由源自不同胚层(内胚层、中胚层和外胚层)的各种组织组成。异位眼组织是一种罕见现象,在其他部位仅有少数病例报道。

病例介绍

这是一名10个月大的男孩,表现为无痛性阴囊肿块。睾丸切除术后,切除的肿块经组织病理学检查证实存在起源于良性睾丸畸胎瘤的葡萄膜和视网膜组织。

讨论

脉络膜和视网膜组织是最常遇到的异位眼组织,而最少观察到的组织是晶状体。大多数报道的异位眼组织病例存在于卵巢畸胎瘤中。之前仅有的2例睾丸畸胎瘤中类似眼组织的病例缺乏如我们病例中明确界定的髓上皮、葡萄膜和视网膜组织。

结论

据我们所知,睾丸畸胎瘤中出现发育中的眼组织极为罕见。在此我们报告一例独特病例,一名婴儿的睾丸畸胎瘤内有成熟的明确界定的眼组织,不应被忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9cf/8885984/c4942d282d61/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9cf/8885984/2717709d2d07/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9cf/8885984/c4942d282d61/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9cf/8885984/2717709d2d07/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9cf/8885984/c4942d282d61/gr2.jpg

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