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Safety and efficacy of a feed additive consisting of lanthanum carbonate octahydrate for dogs (Porus GmbH).一种由八水合碳酸镧组成的犬用饲料添加剂(Porus GmbH)的安全性和有效性。
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Comet Assay Evaluation of Lanthanum Nitrate DNA Damage in C57-ras Transgenic Mice.硝酸镧对 C57-ras 转基因小鼠 DNA 损伤的彗星试验评价。
Biol Trace Elem Res. 2021 Oct;199(10):3728-3736. doi: 10.1007/s12011-020-02500-5. Epub 2021 Jan 5.
2
Clarification of some aspects related to genotoxicity assessment.关于遗传毒性评估相关某些方面的阐释
EFSA J. 2017 Dec 18;15(12):e05113. doi: 10.2903/j.efsa.2017.5113. eCollection 2017 Dec.
3
Guidance on the identity, characterisation and conditions of use of feed additives.饲料添加剂的标识、特性及使用条件指南。
EFSA J. 2017 Oct 17;15(10):e05023. doi: 10.2903/j.efsa.2017.5023. eCollection 2017 Oct.
4
Guidance on the assessment of the safety of feed additives for the target species.目标物种饲料添加剂安全性评估指南。
EFSA J. 2017 Oct 17;15(10):e05021. doi: 10.2903/j.efsa.2017.5021. eCollection 2017 Oct.
5
Case of Chronic Cough Caused by Accidental Inhalation of Lanthanum Carbonate Granules.
Ther Apher Dial. 2020 Apr;24(2):235-236. doi: 10.1111/1744-9987.13396. Epub 2019 Aug 7.
6
Evaluation of the potential genotoxicity of the phosphate binder lanthanum carbonate.碳酸镧磷酸盐结合剂潜在遗传毒性的评估。
Mutagenesis. 2005 Jan;20(1):29-37. doi: 10.1093/mutage/gei003. Epub 2004 Dec 29.

一种由八水合碳酸镧(Lanthan One)组成的猫用饲料添加剂(Porus GmbH)的安全性和有效性。

Safety and efficacy of a feed additive consisting of lanthanum carbonate octahydrate (Lanthan One) for cats (Porus GmbH).

作者信息

Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Aquilina Gabriele, Anguita Montserrat, Tarrés-Call Jordi, Vettori Maria Vittoria, Galobart Jaume

出版信息

EFSA J. 2022 Feb 24;20(2):e07168. doi: 10.2903/j.efsa.2022.7168. eCollection 2022 Feb.

DOI:10.2903/j.efsa.2022.7168
PMID:35233256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8867530/
Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of lanthanum carbonate octahydrate (Lanthan One) as a zootechnical feed additive for cats. The FEEDAP Panel concluded that lanthanum carbonate octahydrate is safe for cats at the maximum proposed use level of 7,500 mg/kg complete feed. The additive is not irritant to skin or eyes, is not a skin sensitiser and exposure of users by inhalation is considered unlikely. The Panel also concluded that the additive is efficacious as a phosphate binder in adult cats at the minimum proposed conditions of use (1,500 mg/kg complete feedingstuffs).

摘要

应欧盟委员会的要求,欧洲食品安全局被要求就八水合碳酸镧(Lanthan One)作为猫用动物营养饲料添加剂的安全性和有效性发表科学意见。饲料添加剂和产品(FEEDAP)专家小组得出结论,在建议的最高使用水平7500毫克/千克全价饲料的情况下,八水合碳酸镧对猫是安全的。该添加剂对皮肤和眼睛无刺激性,不是皮肤致敏剂,并且认为使用者不太可能通过吸入接触到。专家小组还得出结论,在建议的最低使用条件(1500毫克/千克全价饲料)下,该添加剂作为成年猫的磷酸盐结合剂是有效的。