直肠癌乳房转移：病例报告及文献复习。

Breast metastasis from rectal carcinoma: A case report and review of the literature.

机构信息

Department of Breast Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.

Department of Breast Surgery, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China.

出版信息

Malawi Med J. 2021 Sep;33(3):226-228. doi: 10.4314/mmj.v33i3.11.

DOI:10.4314/mmj.v33i3.11

PMID:35233281

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8843179/

Abstract

BACKGROUND

Metastasis from extramammary primary tumor to breast is extremely rare.

CASE SUMMARY

A 59-year-old woman with 1-year history of rectal cancer presented with asymptomatic breast mass. At 16 months after the diagnosis of rectal mucinous adenocarcinoma, a breast mass was confirmed by ultrasonography and identified by pathology and immunohistochemistry as a metastasis from the rectal cancer. Treatments included chemotherapy (6 cycles: 300 mg irinotecan on day 1, 4.5 mg raltitrexed on day 2, 450 mg bevacizumab on day 3), radiotherapy, and surgical resection. Two years of follow-up examinations (6-months intervals) showed no evidence of recurrence or novel distant metastasis.

CONCLUSION

Breast metastasis from rectal carcinoma is a rare secondary malignancy. Final diagnosis can be established by histopathology and immunohistochemistry.

摘要

背景

来自乳腺外原发肿瘤的转移至乳房是极其罕见的。

病例总结

一位 59 岁女性，患有直肠腺癌 1 年，表现为无症状性乳腺肿块。在直肠黏液腺癌诊断后 16 个月时，超声检查发现了乳腺肿块，并通过病理和免疫组化检查确定为直肠腺癌转移。治疗包括化疗（6 个周期：第 1 天 300 mg 伊立替康，第 2 天 4.5 mg 雷替曲塞，第 3 天 450 mg 贝伐珠单抗）、放疗和手术切除。2 年的随访检查（每 6 个月 1 次）未发现复发或新的远处转移。