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华盛顿州和爱达荷州严重急性呼吸综合征冠状病毒2(SARS-CoV-2)从人类到宠物的家庭传播:负担和风险因素

Household transmission of SARS-CoV-2 from humans to pets in Washington and Idaho: burden and risk factors.

作者信息

Meisner Julianne, Baszler Timothy V, Kuehl Kathryn H, Ramirez Vickie, Baines Anna, Frisbie Lauren A, Lofgren Eric T, DeAvila David M, Wolking Rebecca M, Bradway Dan S, Wilson Hannah, Lipton Beth, Kawakami Vance, Rabinowitz Peter M

机构信息

University of Washington, Seattle, WA, USA.

Washington Animal Disease Diagnostic Laboratory, Washington State University, Pullman, WA, USA.

出版信息

bioRxiv. 2022 Feb 22:2021.04.24.440952. doi: 10.1101/2021.04.24.440952.

Abstract

SARS-CoV-2 is believed to have emerged from an animal reservoir; however, the frequency of and risk factors for inter-species transmission remain unclear. We carried out a community-based study of pets in households with one or more confirmed SARS-CoV-2 infection in humans. Among 119 dogs and 57 cats with completed surveys, clinical signs consistent with SARS-CoV-2 were reported in 20 dogs (21%) and 19 cats (39%). Out of 81 dogs and 32 cats sampled for testing, 40% of dogs and 43% of cats were seropositive, and 5% of dogs and 8% of cats were PCR positive; this discordance may be due to delays in sampling. Respondents commonly reported close human-animal contact and willingness to take measures to prevent transmission to their pets. Reported preventative measures showed a slightly protective trend for both illness and seropositivity in pets, while sharing of beds and bowls had slight harmful effects.

摘要

据信,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)源自动物宿主;然而,跨物种传播的频率和风险因素仍不清楚。我们对家中有一例或多例人类确诊感染SARS-CoV-2的宠物进行了一项基于社区的研究。在119只狗和57只猫完成调查后,报告有20只狗(21%)和19只猫(39%)出现了与SARS-CoV-2一致的临床症状。在81只狗和32只猫中取样检测,40%的狗和43%的猫血清呈阳性,5%的狗和8%的猫PCR呈阳性;这种不一致可能是由于采样延迟所致。受访者普遍报告了人与动物的密切接触以及采取措施防止宠物感染的意愿。报告的预防措施对宠物疾病和血清阳性率均显示出轻微的保护趋势,而共用餐床和碗具则有轻微的有害影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d571/8887074/ff9b56741fc6/nihpp-2021.04.24.440952v2-f0001.jpg

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