Emerg Infect Dis. 2022 Dec;28(12):2425-2434. doi: 10.3201/eid2812.220215. Epub 2022 Oct 26.
SARS-CoV-2 likely emerged from an animal reservoir. However, the frequency of and risk factors for interspecies transmission remain unclear. We conducted a community-based study in Idaho, USA, of pets in households that had >1 confirmed SARS-CoV-2 infections in humans. Among 119 dogs and 57 cats, clinical signs consistent with SARS-CoV-2 were reported for 20 dogs (21%) and 19 cats (39%). Of 81 dogs and 32 cats sampled, 40% of dogs and 43% of cats were seropositive, and 5% of dogs and 8% of cats were PCR positive. This discordance might be caused by delays in sampling. Respondents commonly reported close human‒animal contact and willingness to take measures to prevent transmission to their pets. Reported preventive measures showed a slightly protective but nonsignificant trend for both illness and seropositivity in pets. Sharing of beds and bowls had slight harmful effects, reaching statistical significance for sharing bowls and seropositivity.
SARS-CoV-2 可能源自动物宿主。然而,物种间传播的频率和风险因素仍不清楚。我们在美国爱达荷州开展了一项社区研究,调查了家中有 >1 例人类确诊 SARS-CoV-2 感染的宠物。在 119 只狗和 57 只猫中,有 20 只狗(21%)和 19 只猫(39%)出现了与 SARS-CoV-2 一致的临床症状。在 81 只狗和 32 只猫中采样,40%的狗和 43%的猫呈血清阳性,5%的狗和 8%的猫 PCR 阳性。这种不一致可能是由于采样延迟造成的。受访者通常报告了人与动物的密切接触,并愿意采取措施防止病毒传播给他们的宠物。报告的预防措施表明,对宠物的疾病和血清阳性率有轻微的保护作用,但无统计学意义。共用床和碗具有轻微的有害影响,对于共用碗和血清阳性率达到统计学意义。