Department of Anesthesiology, The First Affiliated Hospital Of University of South China, Hengyang, Hunan, China.
Institute of Pharmacy and Pharmacology, Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, College of Basic Medical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Cell Biol Int. 2022 Jun;46(6):878-882. doi: 10.1002/cbin.11785. Epub 2022 Mar 9.
Xu et al. recently demonstrated that cryptochrome 4 (CRY4) protein, as a light-dependent magnetic receptor, can sense geomagnetic fields to guide night-migratory songbirds' navigation and evolution by the formation of composite radical pairs and electron transport. We aim to comment on CRY4 through radical pairs and electron transport for magnetic sensitive in night-migratory songbirds' migration and evolution. Additionally, we find that the role of magnetic fields is deeply concerning to the scientific community and very enlightening for the diagnosis and treatment of cancer and vascular disease. We believe that this commentary makes a significant contribution to the literature because it elaborates on the importance of the geomagnetic field to night-migratory songbirds and extends the diagnostic and therapeutic value to cancer and vascular disease.
徐等人最近表明,隐花色素 4(CRY4)蛋白作为一种光依赖性磁受体,通过形成复合自由基对和电子传递,感知地磁场来指导夜间迁徙鸣禽的导航和进化。我们旨在通过自由基对和电子传递来评论 CRY4 在夜间迁徙鸣禽迁徙和进化中的磁敏感性。此外,我们发现磁场的作用引起了科学界的深切关注,并且对癌症和血管疾病的诊断和治疗具有重要启示。我们认为,这篇评论文章对文献做出了重要贡献,因为它阐述了地磁场对夜间迁徙鸣禽的重要性,并将诊断和治疗价值扩展到癌症和血管疾病。