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七十和八十多岁老年人急性A型主动脉夹层的手术结果

Surgical outcomes of acute type A aortic dissection in septuagenarians and octogenarians.

作者信息

Nakai Yosuke, Yamada Toshiyuki, Ogawa Shinji, Kamiya Shinji, Saitoh Yuhei, Suda Hisao

机构信息

Department of Cardiovascular Surgery, 38386Nagoya City University Graduate School of Medical Sciences, Japan.

出版信息

Asian Cardiovasc Thorac Ann. 2022 Sep;30(7):772-778. doi: 10.1177/02184923221083369. Epub 2022 Mar 2.

Abstract

BACKGROUND

We studied surgical outcomes of acute type A aortic dissection and compared early and late outcomes between septuagenarians and octogenarians.

METHODS

From 2010 to 2019, we evaluated 254 consecutive patients with acute type A aortic dissection. We performed emergent operations within 48 h of symptom onset for 188 patients, including 59 septuagenarians and 32 octogenarians.

RESULTS

The overall 30-day mortality rate was 8.5% in septuagenarians and 9.4% in octogenarians ( = 1.0). The hospital mortality rate was 10.2% in septuagenarians and 12.5% in octogenarians ( = 0.74). Multivariate analysis identified prolonged ventilation (≥ 72 h) as a significant risk factor for hospital mortality. Being an octogenarian was not significantly associated with hospital mortality. The actuarial survival rate at 5 years was 80.1% in septuagenarians and 58.5% in octogenarians (log-rank  = 0.09). The freedom from aortic event rate at 5 years was 91.0% in septuagenarians and 100% in octogenarians (log-rank  = 0.23).

CONCLUSION

The two groups showed no significant differences in hospital mortality or morbidity. Our tear-oriented strategies might be appropriate for both septuagenarians and octogenarians. Prolonged ventilation (≥ 72 h) was a significant risk predictor for hospital mortality.

摘要

背景

我们研究了急性A型主动脉夹层的手术结果,并比较了七旬老人和八旬老人的早期和晚期结果。

方法

2010年至2019年,我们评估了254例连续的急性A型主动脉夹层患者。我们对188例患者在症状出现后48小时内进行了急诊手术,其中包括59例七旬老人和32例八旬老人。

结果

七旬老人的总体30天死亡率为8.5%,八旬老人为9.4%(P = 1.0)。七旬老人的医院死亡率为10.2%,八旬老人为12.5%(P = 0.74)。多因素分析确定延长通气时间(≥72小时)是医院死亡率的一个重要危险因素。八旬老人与医院死亡率无显著相关性。七旬老人5年的精算生存率为80.1%,八旬老人为58.5%(对数秩检验P = 0.09)。七旬老人5年无主动脉事件发生率为91.0%,八旬老人为100%(对数秩检验P = 0.23)。

结论

两组在医院死亡率或发病率方面无显著差异。我们以撕裂为导向的策略可能适用于七旬老人和八旬老人。延长通气时间(≥72小时)是医院死亡率的一个重要风险预测因素。

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