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温针灸联合高压氧治疗缺血性脑卒中的疗效及其对神经功能的影响。

The Efficacy of Needle-Warming Moxibustion Combined with Hyperbaric Oxygen Therapy for Ischemic Stroke and Its Effect on Neurological Function.

机构信息

Neurorehabilitation Department, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First People's Hospital of Lianyungang, The First Affiliated Hospital of Kangda College of Nanjing Medical University, Lianyungang Clinical College of Nanjing Medical University, Lianyungang, 222002 Jiangsu Province, China.

Acupuncture and Massage Department, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First People's Hospital of Lianyungang, The First Affiliated Hospital of Kangda College of Nanjing Medical University, Lianyungang Clinical College of Nanjing Medical University, Lianyungang, 222002 Jiangsu Province, China.

出版信息

Comput Math Methods Med. 2022 Feb 21;2022:2204981. doi: 10.1155/2022/2204981. eCollection 2022.

Abstract

OBJECTIVE

To elucidate the therapeutic efficacy of needle-warming moxibustion (NWM) combined with hyperbaric oxygen therapy (HBOT) in the treatment of patients with ischemic stroke and its effect on neurological function.

METHODS

One hundred patients with ischemic stroke admitted to the Xuzhou Medical University Affiliated Hospital of Lianyungang from January 2019 to July 2021 were enrolled. Among them, 45 patients treated with NWM were set as the control group, and the rest 55 patients treated by NWM combined with HBOT were included in the research group. The curative effect, neurological deficit score, activity of daily living (ADL), balance ability, and the levels of serum proinflammatory factors in both groups were observed and recorded. Of them, the neurological deficit of patients was evaluated by the National Institutes of Health Stroke Scale (NHISS), the ADL ability was determined by the Barthel index score, and the balance ability was assessed by the Berg balance scale.

RESULTS

The total effective rate of the research group was higher than that of the control group. Better ADL and balance ability and milder neurologic impairment were determined in the research group compared with the control group. After treatment, the secretion levels of proinflammatory factors such as C-reactive protein (CRP), tumor necrosis factor- (TNF-), and interleukin-8 (IL-8) in the serum of patients in the research group were statistically lower than those before treatment and the control group.

CONCLUSIONS

NWM combined with HBOT is effective in the treatment of patients with ischemic stroke, which can not only improve patients' neurological function, ADL, and balance ability but also inhibit serum inflammatory reactions.

摘要

目的

阐明温针灸联合高压氧疗法治疗缺血性脑卒中患者的疗效及其对神经功能的影响。

方法

选取 2019 年 1 月至 2021 年 7 月在徐州医科大学附属医院连云港院区收治的缺血性脑卒中患者 100 例,其中采用温针灸治疗的 45 例患者设为对照组,采用温针灸联合高压氧疗法治疗的 55 例患者设为研究组。观察并记录两组患者的疗效、神经功能缺损评分、日常生活活动能力(ADL)、平衡能力及血清促炎因子水平。其中,患者的神经功能缺损采用美国国立卫生研究院卒中量表(NHISS)评估,ADL 能力采用巴氏指数评分(Barthel index score)判定,平衡能力采用 Berg 平衡量表评估。

结果

研究组的总有效率高于对照组。与对照组相比,研究组患者的 ADL 和平衡能力更好,神经功能缺损程度更轻。治疗后,研究组患者血清中 C 反应蛋白(CRP)、肿瘤坏死因子-(TNF-)和白细胞介素-8(IL-8)等促炎因子的分泌水平明显低于治疗前和对照组。

结论

温针灸联合高压氧疗法治疗缺血性脑卒中患者疗效确切,不仅能改善患者的神经功能、ADL 和平衡能力,还能抑制血清炎症反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e40/8885239/bc4411deee43/CMMM2022-2204981.001.jpg

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