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患有散开不足的甲状腺眼病导致一名老年患者反复跌倒

Thyroid Eye Disease With Divergence Insufficiency Causing Recurrent Falls in an Elderly Patient.

作者信息

Lai Wei Chen, Nguyen Nguyen S, Husain Azam, Rajpal Sachin D, Michael Miriam B

机构信息

Ophthalmology, University of Maryland School of Medicine, Baltimore, USA.

Ophthalmology, Howard University College of Medicine, Washington, DC, USA.

出版信息

Cureus. 2022 Jan 28;14(1):e21695. doi: 10.7759/cureus.21695. eCollection 2022 Jan.

DOI:10.7759/cureus.21695
PMID:35237487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8882349/
Abstract

Recurrent falls are a common cause of morbidity in the elderly population, as more than one-third of individuals aged 65 years or older experience falls each year. Falls remain a multifactorial phenomenon that can potentially result in devastating debilitation and hence require proper medical attention and management. In an elderly patient presenting with recurrent falls, the workup for differential diagnoses remains wide with various causes such as postural hypotension, syncope, seizures, arrhythmia, medication-induced, and cognitive impairment. In this report, we discuss an interesting case of recurrent falls in an elderly woman with hyperthyroidism who was repeatedly found to have unremarkable lab results and negative imaging studies. She was later diagnosed with divergence insufficiency with intermittent esotropia secondary to thyroid ophthalmopathy, which was the cause of her underlying horizontal diplopia contributing to her falls. This can cause blurry vision at further distances, which is observed especially in individuals older than 50 years. Treatment typically involves prism therapy, surgery in refractory patients, and, currently, novel therapy using teprotumumab infusion. The patient was referred to see a strabismus specialist for prism prescription and possible surgical intervention. In elderly patients with a history of recurrent falls, a comprehensive visual exam should be strongly considered, especially for individuals with repeated negative workups, to prevent further testing or procedures.

摘要

反复跌倒在老年人群中是发病的常见原因,因为每年有超过三分之一的65岁及以上老年人会跌倒。跌倒仍然是一种多因素现象,可能会导致严重的身体衰弱,因此需要适当的医疗关注和管理。对于出现反复跌倒的老年患者,鉴别诊断的检查范围仍然很广,病因包括体位性低血压、晕厥、癫痫发作、心律失常、药物引起的以及认知障碍等。在本报告中,我们讨论了一例有趣的病例,一名患有甲状腺功能亢进症的老年女性反复跌倒,其实验室检查结果和影像学检查均无异常。她后来被诊断为甲状腺眼病继发的散开不足伴间歇性内斜视,这是导致其潜在水平性复视并导致跌倒的原因。这会导致远处视物模糊,尤其是在50岁以上的人群中更为明显。治疗通常包括棱镜疗法,难治性患者需进行手术,目前还有使用替普罗单抗输注的新型疗法。该患者被转诊至斜视专科医生处,以开具棱镜处方并可能进行手术干预。对于有反复跌倒病史的老年患者,尤其是那些反复检查结果为阴性的患者,应强烈考虑进行全面的视力检查,以避免进一步的检查或治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438b/8882349/4ad28d35de01/cureus-0014-00000021695-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438b/8882349/beeb1fa005eb/cureus-0014-00000021695-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438b/8882349/4ad28d35de01/cureus-0014-00000021695-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438b/8882349/beeb1fa005eb/cureus-0014-00000021695-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438b/8882349/4ad28d35de01/cureus-0014-00000021695-i02.jpg

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