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在Qa-2耗竭的胸腺细胞培养物中，刀豆蛋白A诱导的胸腺细胞增殖增加以及新的Qa-2抗原表达增加。

Increased Con-A-induced thymocyte proliferation and de novo Qa-2 antigen expression in Qa-2-depleted thymocyte cultures.

作者信息

Penit C, Papiernik M

出版信息

Thymus. 1986;8(1-2):25-32.

PMID:3523855
Abstract

We have recently shown that thymocyte activation is associated with a strong increase of Qa-2 antigen expression. Contrary to what could be predicted from these results, the initial depletion of Qa-2+ cells from PNA- thymocytes increases the Con-A-induced proliferation. Qa-2+ cells not only reappeared after activation, but were enhanced in Qa-2-depleted PNA- cells compared to the control. The newly formed Qa-2+ population contained a higher percentage of Lyt 1+2- cells and thus seems to be different from the Qa-2+ pool initially present.

摘要

我们最近发现，胸腺细胞活化与Qa-2抗原表达的显著增加有关。与从这些结果中预测的情况相反，从PNA-胸腺细胞中最初清除Qa-2+细胞会增加刀豆蛋白A诱导的增殖。Qa-2+细胞不仅在活化后重新出现，而且与对照组相比，在Qa-2缺失的PNA-细胞中数量增加。新形成的Qa-2+群体中Lyt 1+2-细胞的百分比更高，因此似乎与最初存在的Qa-2+细胞库不同。

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