Rainard P
Vet Microbiol. 1986 Apr;11(4):387-92. doi: 10.1016/0378-1135(86)90068-4.
The bacteriostatic activity of bovine lactoferrin (Lf) against mastitic bacteria was assessed with an in vitro microassay. The most susceptible species was Escherichia coli; all of the 35 isolates tested were susceptible to bacteriostasis by apo-Lf (0.1 mg ml-1), although a few strains showed a lower degree of inhibition. Heterogeneity among strains was more pronounced among 10 isolates of Staphylococcus aureus, four of which were apparently unaffected by apo-Lf (1 mg ml-1). Under the same conditions, Streptococcus agalactiae (six isolates) and Str. uberis (five isolates) resisted the bacteriostatic action of apo-Lf.
采用体外微量分析法评估了牛乳铁蛋白（Lf）对乳腺炎相关细菌的抑菌活性。最易受影响的菌种是大肠杆菌；所测试的35株分离菌均对脱铁乳铁蛋白（0.1毫克/毫升）的抑菌作用敏感，不过有少数菌株的抑制程度较低。在10株金黄色葡萄球菌分离菌中，菌株间的异质性更为明显，其中4株显然不受脱铁乳铁蛋白（1毫克/毫升）的影响。在相同条件下，无乳链球菌（6株分离菌）和乳房链球菌（5株分离菌）对脱铁乳铁蛋白的抑菌作用具有抗性。
