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利用两次流行疫情的监测数据描述老年人登革热的临床特征。

Clinical profile of dengue in the elderly using surveillance data from two epidemics.

机构信息

Fundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Laboratório de Epidemiologia Clínica, Rio de Janeiro, RJ, Brasil.

Universidade Estácio de Sá, Faculdade de Medicina, Rio de Janeiro, RJ, Brasil.

出版信息

Rev Soc Bras Med Trop. 2022 Feb 25;55:e0290. doi: 10.1590/0037-8682-0290-2021. eCollection 2022.

Abstract

BACKGROUND

Population aging and mobility have increased the exposure of elderly individuals to dengue. This study evaluated the clinical features of dengue in the elderly during the epidemic (2008 and 2012) and interepidemic (2009 and 2010) periods.

METHODS

This cross-sectional study was based on dengue surveillance data from Rio de Janeiro, Brazil: 2008 (n=31,210), 2009‒2010 (n=2,884), and 2012 (n=30,773). The analysis was stratified by age group (<60 and ≥60 years).

RESULTS

Case-fatality rates were higher in the elderly. In 2008, elderly individuals were found to be more prone to hematuria and thrombocytopenia.

CONCLUSIONS

These results can improve the understanding of dengue in elderly individuals who live in or travel to tropical regions.

摘要

背景

人口老龄化和流动增加了老年人感染登革热的风险。本研究评估了流行期(2008 年和 2012 年)和流行间期(2009 年和 2010 年)老年人登革热的临床特征。

方法

本横断面研究基于巴西里约热内卢的登革热监测数据:2008 年(n=31210)、2009-2010 年(n=2884)和 2012 年(n=30773)。分析按年龄组(<60 岁和≥60 岁)分层。

结果

老年患者的病死率更高。2008 年,老年人更易出现血尿和血小板减少症。

结论

这些结果可以提高对生活或前往热带地区的老年人感染登革热的认识。

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Medicine (Baltimore). 2017 Sep;96(37):e7878. doi: 10.1097/MD.0000000000007878.
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Dengue in the elderly: a review.老年人登革热:综述。
Expert Rev Anti Infect Ther. 2017 Aug;15(8):729-735. doi: 10.1080/14787210.2017.1358610. Epub 2017 Jul 28.
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