el-Salhy M, Lundqvist M, Wilander E
Acta Pathol Microbiol Immunol Scand A. 1986 May;94(3):229-35.
A comparative study of bronchial carcinoids (9 cases) and phaeochromocytomas (8 cases) were performed. Both types of tumour exhibited neuron-specific enolase (NSE) immunoreactivity and an argyrophil reaction, and displayed a few scattered argentaffin and serotonin immunoreactive tumour cells. In addition, four of the nine bronchial carcinoids and six of the eight phaeochromocytomas were S-100 protein immunoreactive. The stained cells were located mainly in the periphery of the tumour cell aggregates and possessed long cytoplasmic processes surrounding unreactive tumour cells. The similarity between the two tumour types, especially in their morphology and S-100 protein immunoreactivity, indicates that bronchial carcinoids, or at least some of them, are histogenetically closely related to phaeochromocytomas and might derive from the peripheral nervous system.
对9例支气管类癌和8例嗜铬细胞瘤进行了对比研究。这两种肿瘤均表现出神经元特异性烯醇化酶（NSE）免疫反应性和嗜银反应，并显示出一些散在的亲银和5-羟色胺免疫反应性肿瘤细胞。此外，9例支气管类癌中的4例和8例嗜铬细胞瘤中的6例呈S-100蛋白免疫反应性。染色细胞主要位于肿瘤细胞聚集区的周边，具有围绕无反应性肿瘤细胞的长细胞质突起。这两种肿瘤类型之间的相似性，尤其是在形态学和S-100蛋白免疫反应性方面，表明支气管类癌，或至少其中一些，在组织发生学上与嗜铬细胞瘤密切相关，可能起源于周围神经系统。
