Kotby Alyaa A, Ebrahim Sahar O S, Al-Fahham Marwa M
Pediatric Department, Pediatric Cardiology Unit, Faculty of Medicine, Ain Shams University, Abbasia 11566, Cairo, Egypt.
Cardiol Young. 2023 Jan;33(1):26-34. doi: 10.1017/S1047951122000129. Epub 2022 Mar 4.
Two-dimensional speckle tracking echocardiography-derived left ventricular longitudinal systolic strain is an important myocardial deformation parameter for assessing the systolic function of the left ventricle. Strain values differ according to the vendor machine and software. This study aimed to provide normal reference values for global and regional left ventricular longitudinal systolic strain in Egyptian children using automated functional imaging software integrated into the General Electric healthcare machine and to study the correlation between the global longitudinal left ventricular systolic strain and age, body size, vital data, and some echocardiographic parameters.
Healthy children (250) aged from 1 to 16 years were included. Conventional echocardiography was done to measure the left ventricular dimensions and function. Automated functional imaging was performed to measure the global and regional peak longitudinal systolic strain.
The global longitudinal strain was -21.224 ± 1.862%. The regional strain was -20.68 ± 2.11%, -21.06 ± 1.84%, and -21.86 ± 2.71% at the basal, mid, and apical segments, respectively. The mean values of the systolic longitudinal strain become significantly more negative from base to apex. Age differences were found as regard to global and regional longitudinal strain parameters but no gender differences. The global peak longitudinal systolic strain correlated positively with age. No correlations were found with either the anthropometric parameters or the vital data.
Age-specific normal values for two-dimensional speckle tracking-derived left ventricular longitudinal regional and global systolic strain are established using automated functional imaging.
二维斑点追踪超声心动图得出的左心室纵向收缩期应变是评估左心室收缩功能的重要心肌变形参数。应变值因供应商的机器和软件而异。本研究旨在使用通用电气医疗设备中集成的自动功能成像软件，提供埃及儿童左心室纵向整体和局部收缩期应变的正常参考值，并研究左心室纵向整体收缩期应变与年龄、体型、生命数据及一些超声心动图参数之间的相关性。
纳入250名年龄在1至16岁的健康儿童。进行常规超声心动图检查以测量左心室尺寸和功能。进行自动功能成像以测量整体和局部纵向收缩期峰值应变。
整体纵向应变为-21.224±1.862%。基底段、中间段和心尖段的局部应变分别为-20.68±2.11%、-21.06±1.84%和-21.86±2.71%。收缩期纵向应变的平均值从基底到心尖显著变得更负。在整体和局部纵向应变参数方面发现了年龄差异，但未发现性别差异。整体纵向收缩期峰值应变与年龄呈正相关。未发现与人体测量参数或生命数据有相关性。
使用自动功能成像建立了二维斑点追踪得出的左心室纵向局部和整体收缩期应变的年龄特异性正常值。
