de la Pena N C, Diaz A, Damel A, Bal E, Puricelli L, Ejden J, de Lustig E S
Biomedicine. 1978 May;28(2):104-8.
The topical action of a combined therapy of human interferon (3000 U/ml) and secretory immunoglobulin IgA (1,5 mg/ml) was studied in 56 patients with herpetic keratitis. The pain and photophobia disappeared within 48 h after the beginning of treatment and a marked reduction of the corneal lesion during the first week of treatment was observed in all the patients. The therapy was effective, with complete healing of the lesion in 94.8% of cases; 72.2% of them healed in less than 15 days. The highest frequency of healing was between 5 and 10 days, and the rest up to 30 days. Humoral, immunological and delayed hypersensitivity studies were carried out in 36 patients.
对56例疱疹性角膜炎患者研究了人干扰素（3000 U/ml）和分泌型免疫球蛋白IgA（1.5 mg/ml）联合治疗的局部作用。治疗开始后48小时内疼痛和畏光症状消失，所有患者在治疗第一周角膜病变均有明显减轻。该治疗有效，94.8%的病例病变完全愈合；其中72.2%在不到15天内愈合。愈合频率最高的是在5至10天之间，其余的在30天内愈合。对36例患者进行了体液、免疫和迟发型超敏反应研究。
