Clabots D, Serrat A
Palmetto General Hospital, 2001 W 68th St, Suite 202, Hialeah, FL 33016, USA.
IDCases. 2022 Feb 11;27:e01445. doi: 10.1016/j.idcr.2022.e01445. eCollection 2022.
, like most nontuberculous mycobacteria, is a pervasive organism. It frequently presents as a healthcare-associated infection. infections are notoriously difficult to treat, requiring multidrug regimens and a prolonged treatment course. The patient is a 39 year old hispanic female with a history of pseudotumor cerebri with ventriculoperitoneal shunt which had recently been removed due to concern for infection. She presented with complaints of headaches, blurry vision, nausea, vomiting, slowed speech, inability to void and difficulty with memory. One month into this hospitalization, a new shunt was placed for symptomatic hydrocephalus. She began to exhibit signs of clinical worsening with confusion and echolalia, so her shunt was removed. Intraoperatively the peritoneal catheter of the shunt was noted to have a viscous secretion around it. Cultures of this fluid and samples from the cerebrospinal fluid grew . Shunt-associated central nervous system infections with are rare and difficult to treat. Treatment of is complicated by inducible macrolide resistance and some inherent resistance to many antibiotics.
与大多数非结核分枝杆菌一样，[具体菌名未给出]是一种广泛存在的微生物。它常表现为与医疗保健相关的感染。[该菌名]感染 notoriously difficult to treat（此处“notoriously difficult to treat”直译为“ notoriously 难以治疗”，可能是“众所周知难以治疗”之意），需要多药联合治疗方案且疗程较长。患者为一名39岁的西班牙裔女性，有假性脑瘤病史且曾行脑室腹腔分流术，近期因担心感染而移除了该分流管。她出现头痛、视力模糊、恶心、呕吐、言语迟缓、排尿困难及记忆力减退等症状。此次住院一个月后，因症状性脑积水放置了新的分流管。她开始出现临床恶化迹象，表现为意识模糊和模仿言语，因此移除了分流管。术中发现分流管的腹腔导管周围有粘性分泌物。该液体培养物及脑脊液样本培养出了[具体菌名未给出]。[具体菌名未给出]引起的分流管相关中枢神经系统感染罕见且难以治疗。[具体菌名未给出]的治疗因可诱导的大环内酯类耐药性及对多种抗生素的一些固有耐药性而变得复杂。
