Busuttil R W, Memsic L D, Quinones-Baldrich W, Hiatt J R, Ramming K P
Am J Surg. 1986 Jul;152(1):75-80. doi: 10.1016/0002-9610(86)90146-7.
The development of a liver transplantation program requires a multidisciplinary approach which can only be provided in a large tertiary referral medical center. Preparation for the clinical program involves training of all team members, both in the animal laboratory and at an established liver transplant center. A special commitment from the medical center to the program is essential and involves medical, nursing, and administrative divisions, blood bank, social service, and operating room personnel, and intensive care unit facilities. With careful planning, a successful liver transplant program can be realized from the onset. In the first 2 years of UCLA's liver transplant program, 62 transplants in 50 patients were performed. The overall survival rate was 72 percent with no operative deaths. Thirty-four of 36 surviving patients have returned to useful, productive lives after orthotopic liver transplantation.
肝移植项目的开展需要多学科协作，而这只有在大型三级转诊医疗中心才能实现。临床项目的准备工作包括对所有团队成员进行培训，培训地点包括动物实验室和已成熟的肝移植中心。医疗中心对该项目的特别投入至关重要，涉及医疗、护理和行政部门、血库、社会服务、手术室人员以及重症监护病房设施。通过精心规划，从一开始就能实现成功的肝移植项目。在加州大学洛杉矶分校肝移植项目的头两年，为50名患者进行了62例移植手术。总体生存率为72%，无手术死亡病例。36名存活患者中有34名在原位肝移植后恢复了有益且有意义的生活。
