Peng Enoch T, Adrean Sean D
Retina Consultants of Orange County, Fullerton, CA, USA.
Department of BioSciences, Rice University, Houston, TX, USA.
Am J Ophthalmol Case Rep. 2022 Feb 11;26:101424. doi: 10.1016/j.ajoc.2022.101424. eCollection 2022 Jun.
To describe a case of marked vision loss in a patient with neovascular age-related macular degeneration after choroidal neovascular membrane (CNV) improvement and stabilization.
An 82-year-old male presented with 20/800 vision having dropped from 20/50 three months prior. He had been undergoing active treatment for exudative macular degeneration over the past seven years, the CNV had stabilized. An extensive ophthalmic workup was performed revealing no CNV progression and no ophthalmic cause was identified for visual loss. An MRI of the brain was obtained, which showed a metastatic brain lesion in the occipital lobe, and subsequent workup determined it originated from an adenosquamous carcinoma of the lung.
When there is unexplained visual loss in an otherwise stable patient with macular degeneration, suspicion for non-retinal related causes of visual loss could alter the morbidity and mortality for patients with systemic diseases.
描述1例新生血管性年龄相关性黄斑变性患者在脉络膜新生血管膜(CNV)改善并稳定后出现明显视力丧失的病例。
一名82岁男性,视力从三个月前的20/50下降至20/800。在过去七年中,他一直在接受渗出性黄斑变性的积极治疗,CNV已稳定。进行了全面的眼科检查,未发现CNV进展,也未确定视力丧失的眼科原因。进行了脑部MRI检查,结果显示枕叶有转移性脑病变,随后的检查确定其起源于肺腺鳞癌。
在黄斑变性病情原本稳定的患者中,若出现无法解释的视力丧失,怀疑非视网膜相关的视力丧失原因可能会改变全身性疾病患者的发病率和死亡率。