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“如此大手术后这正常吗?”一名青少年右颞叶切除术后的记忆主诉

"Is this normal after such a major surgery?" Memory complaint after right temporal lobe excision in an adolescent.

作者信息

Smith Mary Lou

机构信息

University of Toronto, The Hospital for Sick Children, Toronto ON M5G 1X8, Canada.

出版信息

Epilepsy Behav Rep. 2021 Dec 8;18:100515. doi: 10.1016/j.ebr.2021.100515. eCollection 2022.

DOI:10.1016/j.ebr.2021.100515
PMID:35243287
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8857461/
Abstract

Memory deficits are commonly associated with temporal-lobe epilepsy. Memory may worsen after surgical resection of the temporal lobe. Risk factors for decline are structural integrity of the mesial temporal lobe structures and intact pre-operative memory. Subjective memory complaints are influenced by depression or other psychological disorders. A 16-year-old girl underwent resection from the right lateral and medial temporal lobe and after surgery she complained of a significant memory impairment, which was unexpected given her baseline assessment. Before undertaking a neuropsychological assessment, she was referred for a psychiatric consultation which revealed depression, leading to treatment with anditdepressant medication. Over time she also admitted to severe headaches and inadequate sleep. With these issues addressed, assessment indicated memory performance had not changed relative to her preoperative baseline with stability or improvement in memory across longitudinal assessments. This case illustrates the contribution of mood state and other potential factors in contributing to subjective memory complaints.

摘要

记忆缺陷通常与颞叶癫痫有关。颞叶手术切除后记忆可能会恶化。记忆衰退的风险因素是内侧颞叶结构的结构完整性和术前完整的记忆。主观记忆主诉受抑郁或其他心理障碍的影响。一名16岁女孩接受了右侧外侧和内侧颞叶切除术,术后她抱怨出现了严重的记忆障碍,鉴于她的基线评估,这是出乎意料的。在进行神经心理学评估之前,她被转介进行精神科咨询,结果发现患有抑郁症,随后接受了抗抑郁药物治疗。随着时间的推移,她还承认有严重的头痛和睡眠不足。解决这些问题后,评估表明她的记忆表现相对于术前基线没有变化,在纵向评估中记忆稳定或有所改善。这个案例说明了情绪状态和其他潜在因素对主观记忆主诉的影响。

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引用本文的文献

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Editorial.社论。
Epilepsy Behav Rep. 2023 Apr 18;22:100602. doi: 10.1016/j.ebr.2023.100602. eCollection 2023.

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Appl Neuropsychol Child. 2020 Oct-Dec;9(4):292-306. doi: 10.1080/21622965.2020.1750118. Epub 2020 May 6.
2
Temporal lobe surgery and memory: Lessons, risks, and opportunities.颞叶手术与记忆:教训、风险与机遇。
Epilepsy Behav. 2019 Dec;101(Pt A):106596. doi: 10.1016/j.yebeh.2019.106596. Epub 2019 Nov 9.
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Verbal associative memory outcomes in pediatric surgical temporal lobe epilepsy: Exploring the impact of mesial structures.儿童外科颞叶癫痫的言语联想记忆结果:探讨内侧结构的影响。
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Mechanisms of systems memory consolidation during sleep.睡眠期间系统记忆巩固的机制。
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