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迷你经皮肾镜取石术是否会改变儿童肾结石的治疗格局?

Is Mini Percutaneous Nephrolithotomy a Game Changer for the Treatment of Renal Stones in Children?

作者信息

Mahmood Sarwar Noori, Falah Barzy, Ahmed Choman, Fakhralddin Saman, Tawfeeq Hewa

机构信息

University of Sulaimani, Sulaimania, Iraq.

出版信息

Eur Urol Open Sci. 2022 Jan 28;37:45-49. doi: 10.1016/j.euros.2021.12.014. eCollection 2022 Mar.

Abstract

BACKGROUND

Mini percutaneous nephrolithotomy (MPCNL) is a newer surgical procedure that has changed the management of paediatric renal stones.

OBJECTIVE

To evaluate MPCNL morbidity and success rates for renal stones as a function of patient age in a paediatric cohort.

DESIGN SETTING AND PARTICIPANTS

This was a retrospective case series that included 143 consecutive patients younger than 17 yr who underwent MPCNL at our institution between January 2016 and November 2020. The patients were categorised into three different age groups: <6 yr ( = 71, 49.7%), 6-11 yr ( = 44, 30.8%), and 12-17 yr ( = 28, 19.6%). MPCNL was performed in all patients through 16-20Fr tracts.

OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS

The stone-free rate, perioperative complications, tract number, operative time, postoperative haemoglobin change, and hospitalisation time were evaluated for each age group.

RESULTS AND LIMITATIONS

MPCNL was performed in 143 paediatric patients (88 boys and 55 girls; mean age 6.53 yr). The mean stone burden (± standard deviation) was 2.096 ± 1.01 cm in group one, 2.05 ± 1.05 cm in group two, and 3.46 ± 19.94 cm in group three; group three was significantly larger ( = 0.001). After a single MPCNL session, 92.42% of patients experienced complete stone clearance. All age groups were similar in terms of stone-free rate ( = 0.82), hospitalisation time ( = 0.94), postoperative haemoglobin change ( = 0.06), and perioperative complications ( = 0.62). However, stone size ( = 0.009), stone complexity ( = 0.001), number of access points ( = 0.03), and operative time ( = 0.009) were higher in the group aged 12-17 yr.

CONCLUSIONS

MPCNL is an effective and safe procedure in younger as well as older children. Age should not be considered a limiting factor for MPCNL in children, and MPCNL should be considered the primary option for treating paediatric renal stones when PCNL is indicated.

PATIENT SUMMARY

Our results show that surgical removal of kidney stones through an incision in the skin and using miniaturised instruments is an effective and safe procedure for children.

摘要

背景

微创经皮肾镜取石术(MPCNL)是一种较新的外科手术,改变了小儿肾结石的治疗方式。

目的

评估在小儿队列中,MPCNL治疗肾结石的发病率及成功率与患者年龄的关系。

设计、地点和参与者:这是一项回顾性病例系列研究,纳入了2016年1月至2020年11月在我院接受MPCNL的143例17岁以下连续患者。患者被分为三个不同年龄组:<6岁(n = 71,49.7%),6 - 11岁(n = 44,30.8%),以及12 - 17岁(n = 28,19.6%)。所有患者均通过16 - 20Fr通道进行MPCNL。

结局测量和统计分析

评估每个年龄组的结石清除率、围手术期并发症、通道数量、手术时间、术后血红蛋白变化及住院时间。

结果与局限性

143例小儿患者接受了MPCNL(88例男孩和55例女孩;平均年龄6.53岁)。第一组平均结石负荷(±标准差)为2.096±1.01 cm,第二组为2.05±1.05 cm,第三组为3.46±19.94 cm;第三组明显更大(P = 0.001)。单次MPCNL术后,92.42%的患者结石完全清除。所有年龄组在结石清除率(P = 0.82)、住院时间(P = 0.94)、术后血红蛋白变化(P = 0.06)及围手术期并发症(P = 0.62)方面相似。然而,12 - 17岁组的结石大小(P = 0.009)、结石复杂性(P = 0.001)、穿刺点数量(P = 0.03)及手术时间(P = 0.009)更高。

结论

MPCNL在年幼儿童和年长儿童中都是一种有效且安全的手术。年龄不应被视为小儿MPCNL的限制因素,当有经皮肾镜取石术指征时,MPCNL应被视为治疗小儿肾结石的首选方法。

患者总结

我们的结果表明,通过皮肤切口并使用小型化器械手术切除肾结石对儿童来说是一种有效且安全的手术。

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