Kaforau Lydia S K, Tessema Gizachew A, Jancey Jonine, Dhamrait Gursimran, Bugoro Hugo, Pereira Gavin
Faculty of Nursing, Medicine and Health Sciences, Solomon Islands National University, Solomon Islands.
Curtin School of Population Health, Curtin University, 400 Kent St, Bentley, Perth, Western Australia 6102, Australia.
Lancet Reg Health West Pac. 2022 Feb 23;21:100402. doi: 10.1016/j.lanwpc.2022.100402. eCollection 2022 Apr.
Prevalence and exposures of adverse birth outcomes is well studied in low-and-middle-income countries but not well-established for the Pacific Island region. Our study mapped the available evidence on low birth weight (LBW), preterm birth, and small for gestational age (SGA)'s prevalence and their corresponding risks in the region.
We followed the five-staged Arksey and O'Malley's framework with clinicians' consultation in the region. Five scholarly databases and non-indexed studies were searched and extracted data were analysed as numerical and thematic summaries mapping the outcomes and exposures.
We included 20 studies representing 11 Pacific Island countries with the following mean prevalence and associations at 95% confidence interval. Estimated mean prevalence for LBW and preterm births were 12% and 13%, respectively. LBW were associated with malaria in pregnancy [aOR 3.3 (1.00, 10.60)], and betel nut and tobacco [aOR 2.4 (1.00, 6.00)]. Preterm births were associated with malaria in pregnancy [aOR 6.6 (2.46, 17.62)] and maternal obesity [aOR 1.5 (1.00, 2.30)]. SGA were associated with short stature [aOR 1.7 (1.22, 2.41)] and no antenatal bookings [aOR 4.0 (2.12, 7.57)].
Several significant factors identified were malaria infection, obesity, betel nut and tobacco and no antenatal care, also validated by clinicians consulted.
Australia National Health and Medical Research Council.
低收入和中等收入国家对不良出生结局的患病率和暴露因素进行了充分研究,但太平洋岛屿地区尚未明确。我们的研究梳理了该地区低出生体重(LBW)、早产和小于胎龄儿(SGA)的患病率及其相应风险的现有证据。
我们遵循了五阶段的阿克西和奥马利框架,并咨询了该地区的临床医生。检索了五个学术数据库和非索引研究,并对提取的数据进行分析,以数值和主题摘要的形式梳理结局和暴露因素。
我们纳入了代表11个太平洋岛屿国家的20项研究,以下是95%置信区间的平均患病率和关联情况。LBW和早产的估计平均患病率分别为12%和13%。LBW与孕期疟疾相关[aOR 3.3(1.00,10.60)],与槟榔和烟草相关[aOR 2.4(1.00,6.00)]。早产与孕期疟疾相关[aOR 6.6(2.46,17.62)]和孕妇肥胖相关[aOR 1.5(1.00,2.30)]。SGA与身材矮小相关[aOR 1.7(1.22,2.41)]和未进行产前检查相关[aOR 4.0(2.12,7.57)]。
确定的几个重要因素为疟疾感染、肥胖、槟榔和烟草以及未进行产前护理,咨询的临床医生也证实了这些因素。
澳大利亚国家卫生与医学研究委员会。