肺炎克雷伯菌对银离子的耐药机制。
Mechanism of resistance to silver ions in Klebsiella pneumoniae.
作者信息
Kaur P, Vadehra D V
出版信息
Antimicrob Agents Chemother. 1986 Jan;29(1):165-7. doi: 10.1128/AAC.29.1.165.
Abstract
The uptake of silver by an experimentally derived silver-resistant Klebsiella pneumoniae strain was three to four times lower than the uptake by a susceptible strain. Spheroplasts of the two strains showed no difference in uptake. AgNO3 at a concentration of 40 micrograms/ml decreased the succinate dehydrogenase activity in susceptible and resistant strains by 100 and 18%, respectively. More than one resistance mechanism may be involved.
摘要
一株通过实验获得的对银具有抗性的肺炎克雷伯菌对银的摄取量比敏感菌株低三到四倍。两种菌株的原生质球在摄取方面没有差异。浓度为40微克/毫升的硝酸银分别使敏感菌株和抗性菌株的琥珀酸脱氢酶活性降低了100%和18%。可能涉及不止一种抗性机制。
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