Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Elaine Marieb Center for Nursing and Engineering Innovation, Institute for Applied Life Sciences and College of Nursing, Nursing and Engineering Center for Innovation, University of Massachusetts, Amherst, Massachusetts, USA.
Periodontol 2000. 2022 Jun;89(1):51-58. doi: 10.1111/prd.12423. Epub 2022 Mar 4.
Nonventilator hospital-associated pneumonia has recently emerged as an important preventable hospital-associated infection, and is a leading cause of healthcare-associated infection. Substantial accumulated evidence links poor oral health with an increased risk of pneumonia, which can be caused by bacterial, viral, or fungal pathogens, each with their own distinct mechanisms of transmission and host susceptibility. These infections are frequently polymicrobial, and often include microbes from biofilms in the oral cavity. Evidence documenting the importance of oral care to prevent nonventilator hospital-associated pneumonia is continuing to emerge. Reduction of oral biofilm in these populations will reduce the numbers of potential respiratory pathogens in the oral secretions that can be aspirated, which in turn can reduce the risk for pneumonia. This review summarizes up-to-date information on the role of oral care in the prevention of nonventilator hospital-associated pneumonia.
最近，非呼吸机相关性医院获得性肺炎已成为一种重要的可预防医院获得性感染，也是导致医疗保健相关性感染的主要原因。大量累积证据表明，口腔健康不良与肺炎风险增加有关，肺炎可由细菌、病毒或真菌病原体引起，每种病原体都有其独特的传播机制和宿主易感性。这些感染通常是多种微生物的，并且经常包括口腔生物膜中的微生物。有证据表明口腔护理对预防非呼吸机相关性医院获得性肺炎的重要性仍在不断涌现。减少这些人群中的口腔生物膜将减少可被吸入的口腔分泌物中潜在呼吸道病原体的数量，从而降低肺炎的风险。这篇综述总结了口腔护理在预防非呼吸机相关性医院获得性肺炎中的最新信息。
