扎普司特（M&B 22,948，一种口服吸收的肥大细胞稳定剂）对儿童运动诱发性哮喘的影响。
The effect of zaprinast (M&B 22,948, an orally absorbed mast cell stabilizer) on exercise-induced asthma in children.
作者信息
Reiser J, Yeang Y, Warner J O
出版信息
Br J Dis Chest. 1986 Apr;80(2):157-63. doi: 10.1016/0007-0971(86)90036-7.
PMID:3524648
Abstract
We conducted a placebo controlled, double-blind trial on the effect of a single dose of zaprinast (M&B 22,948, an orally active mast cell stabilizer) on exercise-induced asthma in 15 children. We demonstrated no prophylactic effect on the whole group. A trend towards effectiveness was shown when the results for children whose asthma was not steroid dependent were analysed alone.
摘要
我们对15名儿童进行了一项安慰剂对照双盲试验，以研究单剂量扎普司特（M&B 22,948，一种口服活性肥大细胞稳定剂）对运动诱发性哮喘的影响。我们证明对整个组没有预防作用。单独分析哮喘不依赖类固醇的儿童的结果时，显示出有疗效的趋势。
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