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桡动脉内自行注射碾碎吗啡片后发生急性肢体缺血:红外热成像在评估组织灌注中的作用。

Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrared Thermography in the Assessment of Tissue Perfusion.

机构信息

Faculty of Medicine, University of Brasilia, Brasília, DF, Brazil.

Department of Internal Medicine, Santa Maria Regional Hospital, Brasília, DF, Brazil.

出版信息

Am J Case Rep. 2022 Mar 5;23:e935336. doi: 10.12659/AJCR.935336.

Abstract

BACKGROUND This article presents a case involving complications after intentional injection of crushed tablets into the arterial circulation, its diagnosis, and the treatment adopted. The diagnosis process illustrates the potential of techniques based on thermal imaging as tools to assess tissue perfusion. Inadvertent intravenous injection of crushed tablets is more common, but there are few reports on arterial circulation, and no studies were found on the self-injection of crushed morphine tablets, particularly into the radial artery. CASE REPORT A 51-year-old man with alcoholism and a history of illegal drug usage intentionally self-injected 3 crushed morphine tablets into his right radial artery. The patient progressed with compartment syndrome, requiring decompressive fasciotomy of the right forearm and ischemia of the right fingers, which were amputated. He presented with rhabdomyolysis and required dialysis. The patient agreed to full heparinization, corticotherapy, and the use of nitroglycerin and prostaglandin E1. Due to the progression of the necrotic area, the patient underwent proximal phalanx excision and surgical reconstruction of the right-hand remnant. CONCLUSIONS The injection of morphine tablets into circulation caused severe complications, which led to the excision of the proximal phalanx and the surgical reconstruction of the remnant of the right hand. In the present case, infrared thermography proved to be an effective method in assessing tissue perfusion.

摘要

背景

本文介绍了一例因将片剂压碎后注入动脉循环而导致并发症的病例,包括其诊断和所采取的治疗措施。该诊断过程说明了基于热成像技术评估组织灌注的潜力。意外将压碎的片剂静脉注射更为常见,但涉及动脉循环的报道较少,关于将压碎的吗啡片剂自行注射入桡动脉的研究则更为罕见。

病例报告

一名 51 岁男性,有酗酒史和非法药物使用史,故意将 3 片压碎的吗啡片注入其右侧桡动脉。患者进展为筋膜间室综合征,需要进行右侧前臂减压性筋膜切开术和右手手指缺血,导致右手手指被截肢。他出现横纹肌溶解症,需要进行透析。患者同意接受充分的肝素化、皮质激素治疗以及使用硝酸甘油和前列腺素 E1。由于坏死区域的进展,患者接受了近节指骨切除术和右手残端的手术重建。

结论

将吗啡片剂注入循环系统导致了严重的并发症,导致近端指骨切除和右手残端的手术重建。在本病例中,红外热成像被证明是评估组织灌注的有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0e8/8905963/358496673430/amjcaserep-23-e935336-g001.jpg

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