Bodh Vishal, Kumar Rajesh, Sharma Rajesh, Sharma Brij, Sachdeva Amit, Azad Ramesh
Department of Gastroenterology, Indira Gandhi Medical College, Shimla, 171 001, India.
Department of Community Medicine, Indira Gandhi Medical College, Shimla, 171 001, India.
Indian J Gastroenterol. 2022 Apr;41(2):143-148. doi: 10.1007/s12664-021-01216-1. Epub 2022 Mar 5.
Sensorineural hearing loss (SNHL) has been reported in association with inflammatory bowel disease (IBD). However, SNHL as an extraintestinal manifestation of IBD is frequently underreported. In the present study, we compared the prevalence and severity of SNHL among patients with IBD-ulcerative colitis (IBD-UC) in remission with controls to find out any association between SNHL and IBD-UC in remission compared to controls.
This single-center hospital-based prospective observational study included outdoor patients with IBD-UC in remission and healthy age- and sex-matched controls. Eligible patients and healthy participants were subjected to a battery of audiological tests (otoscopy, tympanometry and pure tone audiometry [PTN]) after thorough systemic and ear, nose and throat (ENT) examination.
A total of 100 patients were enrolled in the study: 50 in IBD-UC in the remission group and 50 in the control group. None of the demographic variables (age, gender, residence and habits) were significantly different between the two groups. Otoscopy and tympanometry were normal in all patients and controls. The difference between the two groups in respect to frequency and severity of SNHL on PTA and in respect to unilateral and bilateral distribution of the hearing loss was not statistically significant.
There is no statistically significant difference in frequency and severity of SNHL between patients with ulcerative colitis in remission and healthy age- and sex-matched controls.
据报道，感音神经性听力损失（SNHL）与炎症性肠病（IBD）有关。然而，作为IBD肠外表现的SNHL经常未被充分报道。在本研究中，我们比较了缓解期IBD-溃疡性结肠炎（IBD-UC）患者与对照组中SNHL的患病率和严重程度，以找出缓解期IBD-UC与对照组相比SNHL之间的任何关联。
这项基于单中心医院的前瞻性观察性研究纳入了缓解期IBD-UC的门诊患者以及年龄和性别匹配的健康对照。在进行全面的全身及耳鼻喉（ENT）检查后，符合条件的患者和健康参与者接受了一系列听力学测试（耳镜检查、鼓室图和纯音听力测定[PTN]）。
本研究共纳入100名患者：缓解组中IBD-UC患者50名，对照组50名。两组之间的任何人口统计学变量（年龄、性别、居住地和习惯）均无显著差异。所有患者和对照的耳镜检查和鼓室图均正常。两组在PTA上SNHL的频率和严重程度以及听力损失的单侧和双侧分布方面的差异无统计学意义。
缓解期溃疡性结肠炎患者与年龄和性别匹配的健康对照组在SNHL的频率和严重程度上无统计学显著差异。
