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菲律宾一家三级医院中Buschke-Lowenstein肿瘤手术治疗的结果

Outcomes of surgical management of buschke-lowenstein tumor in a Philippine tertiary hospital.

作者信息

Manlubatan Sofia Isabel T, Onglao Mark Augustine S, Tampo Mayou Martin T, Lopez Marc Paul J

机构信息

Division of Colorectal Surgery, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.

出版信息

Ann Coloproctol. 2022 Feb;38(1):82-87. doi: 10.3393/ac.2020.00731.0104. Epub 2022 Feb 23.

Abstract

Buschke-Lowenstein tumor (BLT) is a sexually transmitted infection (STI) caused by the human papillomavirus. This study investigated the profile, management, and outcomes of patients who underwent surgery for BLT from 2015 to 2019 at the Philippine General Hospital. Seven patients underwent surgery for BLT. All were male, with ages ranging from 21 to 41 years. Presenting symptoms were anal mass, foul-smelling discharge, pain, bleeding, and pruritus. All were positive for human immunodeficiency virus. All admitted to having engaged in both insertive and receptive anal intercourse, with multiple partners. All underwent excision with healing by secondary intention. Two had recurrence of warts. Four had an anal stricture. Of these, 3 underwent anal dilatation, while 1 had to undergo proximal bowel diversion. One had intraepithelial carcinoma without dermal invasion on histopathologic analysis. BLT is a rare STI characterized by local aggressiveness but with low malignant potential. Wide excision remains to be the mainstay of treatment.

摘要

Buschke-Lowenstein肿瘤(BLT)是一种由人乳头瘤病毒引起的性传播感染。本研究调查了2015年至2019年在菲律宾总医院接受BLT手术患者的情况、治疗及预后。7例患者接受了BLT手术。均为男性,年龄在21至41岁之间。主要症状为肛门肿物、恶臭分泌物、疼痛、出血和瘙痒。所有患者人类免疫缺陷病毒检测均为阳性。所有患者均承认有插入式和接受式肛交行为,且有多个性伴侣。所有患者均接受了二期愈合的切除术。2例出现疣复发。4例出现肛门狭窄。其中3例接受了肛门扩张术,1例不得不接受近端肠造口术。1例经组织病理学分析为无真皮侵犯的上皮内癌。BLT是一种罕见的性传播感染,具有局部侵袭性但恶性潜能较低。广泛切除仍然是主要的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f8b/8898636/b1c96a8c23dd/ac-2020-00731-0104f1.jpg

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