Division of Pulmonary and Critical Care Medicine, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Eka Kotebe General Hospital, Addis Ababa Ethiopia.
Ethiop J Health Sci. 2022 Jan;32(1):205-208. doi: 10.4314/ejhs.v32i1.21.
Since the outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV2) in December 2019, there have been some case reports of Coronavirus disease 19 (COVID 19) associated Guillain-Barré Syndrome (GBS). GBS is an inflammatory polyradiculoneuropathy associated with numerous viral and bacterial infections. Here we describe the case of an Ethiopian man with a typical clinical and electrophysiological manifestation of GBS.
A 70-year-old male presented with four days history of progressive and ascending bilateral limbs weakness which end up with respiratory failure. He had an antecedent headache, loss of appetite, and generalized fatigue. Electrophysiological studies showed Acute Motor and Sensory Axonal Neuropathy whereas and cerebrospinal fluid analysis revealed albuminocytologic dissociation with positive preintubation SARS CoV2 test. He was treated with supportive care and recovered successfully.
This case illustrates one of the few occasions when patients with mild COVID-19 develop severe neurologic manifestations. Seemingly, early identification and management can improve clinical outcomes. We would like to emphasize the need to consider screening for SARS CoV-2 in patients presenting with GBS.
自 2019 年 12 月严重急性呼吸综合征冠状病毒 2 型（SARS-CoV2）爆发以来，已有一些关于 COVID-19 相关格林-巴利综合征（GBS）的病例报告。GBS 是一种与多种病毒和细菌感染相关的炎症性多神经根神经病。在这里，我们描述了一例埃塞俄比亚男性的典型临床和电生理表现的 GBS。
一名 70 岁男性，因进行性和上升性双侧肢体无力，最终导致呼吸衰竭，发病 4 天。他有前驱性头痛、食欲不振和全身疲劳。电生理研究显示急性运动和感觉轴索性神经病，而脑脊液分析显示白蛋白细胞分离，且 SARS-CoV2 检测呈阳性。他接受了支持性治疗并成功康复。
本病例说明了少数 COVID-19 轻症患者出现严重神经系统表现的情况之一。显然，早期识别和管理可以改善临床结局。我们想强调在出现 GBS 的患者中筛查 SARS-CoV-2 的必要性。
