抗病毒类黄酮是解决新冠疫情问题的方法之一吗？
Are Antiviral Flavonoids Part of the Solution to the COVID-19 Pandemic?
作者信息
Pizzorno Joseph
出版信息
Integr Med (Encinitas). 2021 Dec;20(6):8-13.
Abstract
The relentless continuation of the COVID-19 (coronavirus disease 2019) pandemic clearly indicates the need to broaden our approach to this serious, worldwide problem. An important factor that has received little attention is the protective role of dietary antiviral flavonoids. Many flavonoids have been shown through molecular docking assays, as well as in silico studies, and in vitro and in vivo studies to inhibit virtually every mechanism needed by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) to penetrate cells and hijack molecular processes. These inhibitory effects have shown clinical benefit in a few preliminary studies. In this editorial I present research which makes the case for dietary flavonoids as part of the solution to the COVID-19 pandemic.
摘要
2019冠状病毒病（COVID-19）大流行的持续蔓延清楚地表明，我们需要拓宽应对这一严重全球性问题的方法。一个很少受到关注的重要因素是膳食中抗病毒类黄酮的保护作用。通过分子对接试验、计算机模拟研究以及体外和体内研究表明，许多类黄酮实际上可以抑制严重急性呼吸综合征冠状病毒2（SARS-CoV-2）侵入细胞和操纵分子过程所需的各种机制。在一些初步研究中，这些抑制作用已显示出临床益处。在这篇社论中，我介绍了一些研究，这些研究证明膳食类黄酮可作为解决COVID-19大流行问题的一部分。
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