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野生蜂蜜中毒:来自尼泊尔西部的一例病例报告。

Wild honey poisoning: A case report from western Nepal.

作者信息

Paudel Anuj Krishna, Pokhrel Amrit, Gaire Suman, Paudel Ananta Hari, Poudel Sujan, Paudel Suman, Cueva Wilson, Michel George J

机构信息

Intensive Care Unit (ICU) Metrocity Hospital and Research Center Pokhara Nepal.

Emergency Department Metrocity Hospital and Research Center Pokhara Nepal.

出版信息

Clin Case Rep. 2022 Mar 1;10(3):e05527. doi: 10.1002/ccr3.5527. eCollection 2022 Mar.

Abstract

Wild honey has been used for several purposes in South-Asia and Eastern Europe since long ago. One of the commonest is medicinal purposes, especially for gastrointestinal disorders (peptic ulcer disease, dyspepsia, and gastritis), hypertension, and an aphrodisiac (sexual stimulant). However, honey produced from the nectar of few rhododendron species contains a toxin known as grayanotoxin, which acts on the sodium channel and prevents its inactivation leading to vagal activation, causing hypotension and bradycardia. Here, we report a case of 55 years woman who reported to our Emergency Department with complaints of dizziness and vomiting as well as bradycardia and hypotension. Most of the cases of wild honey poisoning resolve within the first 24 h, but in our case, the symptoms persisted for 72 h. So, we must observe patients for 72 h as some cases may last longer. Timely management of the patient can prevent fatal complications.

摘要

自古以来,野生蜂蜜在南亚和东欧就有多种用途。最常见的用途之一是药用,特别是用于治疗胃肠道疾病(消化性溃疡、消化不良和胃炎)、高血压以及作为一种壮阳药(性兴奋剂)。然而,少数杜鹃花品种花蜜所产的蜂蜜含有一种名为“木藜芦毒素”的毒素,它作用于钠通道并阻止其失活,导致迷走神经激活,引起低血压和心动过缓。在此,我们报告一例55岁女性患者,她因头晕、呕吐以及心动过缓和低血压到我院急诊科就诊。大多数野生蜂蜜中毒病例在最初24小时内可缓解,但在我们这个病例中,症状持续了72小时。所以,我们必须对患者观察72小时,因为有些病例可能持续时间更长。对患者进行及时治疗可预防致命并发症。

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