Kan Takanobu, Takahagi Shunsuke, Matsubara Daiki, Murakami Emi, Kawai Mikio, Hide Michihiro, Tanaka Akio
Department of Dermatology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Regen Ther. 2022 Feb 17;19:154-157. doi: 10.1016/j.reth.2022.01.007. eCollection 2022 Mar.
Cultured epidermal autografts (CEAs) are used to treat extensive burns, giant congenital melanocytic nevi, and epidermolysis bullosa, but information about the long-term clinical course after CEA transplantation is scarce. Here we report 10 years' progress of a 7-year-old Japanese girl who suffered from a scald burn injury affecting 80% of her total body surface area and was treated with CEA transplantation. The skin of a child with extensive burns treated with CEAs appeared soft and of a good texture, even after 10 years, and recovery of skin pigmentation and scar condition were better at sites with a combination of CEAs and autologous skin grafts than those with CEAs alone.