Innovation Center for Neurological Disorders, Department of Neurology, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, China.
J Alzheimers Dis. 2022;87(1):155-160. doi: 10.3233/JAD-215565.
Capgras syndrome (CS) was usually considered a symptom of a functional disorder in the young, most commonly schizophrenia, or an organic disorder in the elderly. The occurrence of CS among early-onset Alzheimer's disease (EOAD) is extremely rare. We describe a case in which the unrecognition of CS as part of EOAD resulted in a wrong psychiatric diagnosis and inappropriate treatment. This paper aims to acknowledge CS as an early or core manifestation and highlight EOAD as a differential diagnosis of mental disorders in young people, even without a remarkable family history.
卡普格拉综合征（CS）通常被认为是年轻人功能性紊乱的一种症状，最常见于精神分裂症，或老年人的器质性紊乱。早发性老年痴呆症（EOAD）中 CS 的发生极为罕见。我们描述了一个病例，CS 未被识别为 EOAD 的一部分，导致了错误的精神科诊断和不适当的治疗。本文旨在承认 CS 是早发性或核心表现，并强调 EOAD 是年轻人精神障碍的鉴别诊断，即使没有显著的家族史。
