From the Department of Anaesthesiology and Reanimation (Pehlıvan, Gergın, Bayram, Biçer, Aksu); and from the Department of Pediatric Gastroenterology (Altay, Arslan), Medical Faculty, Erciyes University, Kayseri, Turkey.
Saudi Med J. 2022 Mar;43(3):275-282. doi: 10.15537/smj.2022.43.3.20210784.
To investigate the rate of laryngospasm with sedation during the esophagogastroduodenoscopy (EGD) procedure in children exposed to passive smoking and to examine the frequency of complications due to laryngospasm.
A single-blind, prospective, observational study with a total of 518 patients evaluated according to the American Society of Anesthesiologists (ASA) physical status as classification I-II, aged between 1-18 years, and planned to undergo an EGD procedure, were included. Age, gender, weight, ASA assessment, exposure to smoking (the mother, the father, both parents were smokers, or not exposed to smoking), drug doses used in sedation, and anesthesia-related complications, such as cough, decrease in oxygen saturation, and laryngospasm were recorded.
Of the 518 patients included in the study, 213 had no smoking exposure history. Oxygen saturation did not decrease below 90% in patients who did not have any smoking exposure. In addition, no laryngospasm was observed in this group. However, 4 (11.4%) of 31 patients whose mother only smoked, 10 (5.1%) of 187 child patients whose father only smoked, and 12 (16.4%) of 61 patients whose mother and father both smoked experienced laryngospasm during the procedure.
The rate of cough, laryngospasm, and hypoxia development increased during the sedation carried out in the EGD procedure in children who were exposed to passive smoke..
调查在接受被动吸烟的儿童中，行食管胃十二指肠镜检查（EGD）时镇静时发生喉痉挛的比率，并检查因喉痉挛引起的并发症的频率。
一项单盲、前瞻性、观察性研究，共纳入 518 例患者，根据美国麻醉医师协会（ASA）的身体状况进行分类，分为 I-II 级，年龄在 1-18 岁之间，计划行 EGD 检查。记录年龄、性别、体重、ASA 评估、吸烟暴露（母亲、父亲、父母双方均吸烟或未吸烟）、镇静中使用的药物剂量以及与麻醉相关的并发症，如咳嗽、血氧饱和度下降和喉痉挛。
在纳入的 518 例患者中，有 213 例无吸烟暴露史。无吸烟暴露史的患者血氧饱和度未降至 90%以下。此外，该组未观察到喉痉挛。然而，在仅母亲吸烟的 31 例患者中，有 4 例（11.4%）发生喉痉挛，在仅父亲吸烟的 187 例儿童患者中，有 10 例（5.1%）发生喉痉挛，在母亲和父亲均吸烟的 61 例患者中，有 12 例（16.4%）发生喉痉挛。
在接受被动吸烟的儿童中，在 EGD 检查过程中进行镇静时，咳嗽、喉痉挛和缺氧的发生率增加。
