Li Fu-Juan, Gao Li, Li Ling-Yun, Zheng Lan-Xiang, Tao Hong, Yang Gui-Qin
School of Geography and Planning, Ningxia University, Yinchuan 750021, China.
China-Arab Joint International Research Laboratory for Featured Resources and Environmental Governance in Arid Regions, Yinchuan 750021, China.
Huan Jing Ke Xue. 2022 Mar 8;43(3):1394-1403. doi: 10.13227/j.hjkx.202104186.
Solid-phase extraction and ultra-high performance liquid chromatography-electrostatic field orbit hydrazine mass spectrometry were used to detect and analyze the contamination of nine antibiotics including sulfonamides, tetracyclines, macrolides, quinolones, and lincomycin in the third drain of Ningxia. Correlations between the antibiotic concentration and water quality indexes were explored, and the ecological risks were evaluated. The results showed that seven antibiotics were detected in the third drain and its confluent stream, with the total concentrations of 14.91-153.48 ng·L and ND-39.37 ng·L, respectively. The detection ratios of clarithromycin, levofloxacin, ciprofloxacin, and lincomycin were 100% in the third drain. The highest-concentration antibiotic was levofloxacin (0.84-94.12 ng·L), followed by lincomycin (11.15-48.13 ng·L). Based on the spatial distribution analysis, after flowing through Pingluo County, total antibiotic concentrations in the third drain increased significantly and showed an increasing trend. The maximum concentration appeared in the Huinong section and showed a decreasing trend downstream. The total concentration of antibiotics before flowing into the Yellow River was 20.26 ng·L. Correlation analysis showed that levofloxacin was significantly positively correlated with NH-N and TN (<0.01), erythromycin was significantly correlated with TN, and clarithromycin was significantly correlated with both NH-N and TN (<0.05), which indicated that water quality index was closely related to antibiotic concentration. The results of the ecological risk assessment showed that levofloxacin and clarithromycin in the third drain posed certain ecological risks.
采用固相萃取和超高效液相色谱-静电场轨道肼质谱联用技术，对宁夏第三排水沟中磺胺类、四环素类、大环内酯类、喹诺酮类和林可霉素等9种抗生素的污染状况进行检测分析。探讨抗生素浓度与水质指标之间的相关性，并评估其生态风险。结果表明，在第三排水沟及其汇流处共检测出7种抗生素，总浓度分别为14.91153.48 ng·L和ND39.37 ng·L。第三排水沟中克拉霉素、左氧氟沙星、环丙沙星和林可霉素的检出率均为100%。浓度最高的抗生素为左氧氟沙星（0.8494.12 ng·L），其次是林可霉素（11.1548.13 ng·L）。基于空间分布分析，第三排水沟流经平罗县后，抗生素总浓度显著升高且呈上升趋势。最高浓度出现在惠农段，下游呈下降趋势。流入黄河前抗生素总浓度为20.26 ng·L。相关性分析表明，左氧氟沙星与NH-N和TN显著正相关（<0.01），红霉素与TN显著相关，克拉霉素与NH-N和TN均显著相关（<0.05），表明水质指标与抗生素浓度密切相关。生态风险评估结果表明，第三排水沟中的左氧氟沙星和克拉霉素存在一定的生态风险。
