Calandria L, Paciel J, Bruno J, Martini M, Vignale R, Civila E
Med Cutan Ibero Lat Am. 1986;14(3):163-5.
Subsets of peripheral blood lymphocytes were studied in 19 patients with alopecia areata. The results shows: a decreased Tm/Tg ratio, decreased number of OKT4+ cells, increased OKT8+ cells, decreased OKT4+/OKT8+ cell ratio. Total lymphocytes, T cells, Tm cells, Tg cells, T DR+ cells and B lymphocytes were normal. The results are similar to those founded in autoimmune diseases and suggest the existence of an immunopathogenic mechanism in these disease.
对19例斑秃患者的外周血淋巴细胞亚群进行了研究。结果显示:Tm/Tg比值降低,OKT4+细胞数量减少,OKT8+细胞增多,OKT4+/OKT8+细胞比值降低。总淋巴细胞、T细胞、Tm细胞、Tg细胞、T DR+细胞和B淋巴细胞均正常。这些结果与自身免疫性疾病中的发现相似,提示这些疾病中存在免疫致病机制。