Gu S Q, Ros A M, Thyresson N, Wasserman J
Acta Derm Venereol. 1981;61(2):125-9.
T-lymphocyte subpopulations and antibody-dependent, cell-mediated cytotoxicity (ADCC) were studied in patients with alopecia areata and universalis. The proportions of T-cells with the receptors for IgG (Tg) and T-cells with receptor for IgM (Tm) were determined in 16 cases. The ADCC of unfractionated lymphocytes was examined in 5 cases. A higher proportion of Tg-cells (T-cell with low affinity for sheep red cells) and a more pronounced ADCC of the peripheral lymphocytes were found in patients with alopecia areata and universalis than in age- and sex-matched normal donors.
对斑秃和全秃患者的T淋巴细胞亚群及抗体依赖性细胞介导的细胞毒性(ADCC)进行了研究。测定了16例患者中具有IgG受体的T细胞(Tg)和具有IgM受体的T细胞(Tm)的比例。检测了5例患者未分离淋巴细胞的ADCC。与年龄和性别匹配的正常供者相比,斑秃和全秃患者中Tg细胞(对绵羊红细胞亲和力低的T细胞)比例更高,外周淋巴细胞的ADCC更明显。